Ultra stretchable, tough, elastic and transparent hydrogel skins integrated with intelligent sensing functions enabled by machine learning algorithms

Wu, Meng; Pan, Mingfei; Qiao, Chenyu; Ma, Yuhao; Yan, Bin; Yang, Wenshuai; Peng, Qiyu; Han, Linbo; Zeng, Hongbo

doi:10.1016/j.cej.2022.138212

Cited by 48 publications

(28 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to this, UV/strain dual-responsive hydrogels can also monitor UV intensity outdoors. The hydrogel prepared in this study can be applied to different fields due to its remarkable properties, − such as flexible wearable devices, copy paper, , and dual-response interactive devices. , …”

Section: Discussionmentioning

confidence: 99%

Dual-Stimuli-Responsive and Anti-Freezing Conductive Ionic Hydrogels for Smart Wearable Devices and Optical Display Devices

Lei

Xiao

Shao

et al. 2023

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

Stimuli-responsive hydrogels are a class of important materials for the preparation of flexible sensors, but the development of UV/stress dual-responsive ion-conductive hydrogels with excellent tunability for wearable devices remains a major challenge. In this study, a dual-responsive multifunctional ion-conductive hydrogel (PVA-GEL-GL-Mo7) with high tensile strength, good stretchability, outstanding flexibility, and stability is successfully fabricated. The prepared hydrogel has an excellent tensile strength of 2.2 MPa, high tenacity of 5.26 MJ/m3, favorable extensibility (522%), and high transparency of 90%. Importantly, the hydrogels have dual responsiveness to UV light and stress, allowing it to be used as a wearable device while responding differently to the UV intensity of different outdoor environments (hydrogels can show different levels of color when exposed to different light intensities of UV light) and can remain flexible at −50 and 85 °C (sensing at both −25 and 85 °C). Therefore, the hydrogels developed in this study have good prospects in different applications, such as flexible wearable devices, duplicate paper, and dual-responsive interactive devices.

show abstract

Section: Discussionmentioning

confidence: 99%

Dual-Stimuli-Responsive and Anti-Freezing Conductive Ionic Hydrogels for Smart Wearable Devices and Optical Display Devices

Lei

Xiao

Shao

et al. 2023

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

show abstract

“…However, these high-toughness hydrogels are usually limited by their self-adhesiveness. Therefore, hydrogels need to be adhered to the skin using external adhesives (such as Scotch tape or 3M adhesives). , Incomplete contact between the hydrogel and skin leads to insufficient sensitivity and accuracy in obtaining human physiological signals. Therefore, design and synthesis of high-strength and self-adhesive hydrogels are urgently required.…”

Section: Introductionmentioning

confidence: 99%

Ultra-adhesive Poly(acrylic acid)-Based Hydrogel as a Flexible Sensor for Capturing Human-Motion Signal

Gao

Zhang

et al. 2023

ACS Appl. Polym. Mater.

View full text Add to dashboard Cite

Conductive hydrogels are widely applied in wearable sensors, soft robotics, and human-interactive devices owing to their unique physicochemical properties. Herein, we prepared an ultra-adhesive poly(acrylic acid)/Fe b /Li 2 SO 4c hydrogel. The maximum peeling forces of the hydrogel with respect to an aluminum substrate and a titanium surface were 1380 and 1619 N•m −1 , respectively. The elongation at break of the hydrogel was 2450%, and the breaking stress was 98 kPa. Owing to the synergistic effect of the −COOH−Fe 3+ complex and H bonds, the prepared hydrogels exhibited self-healing properties. Because of the presence of lithium sulfate, the hydrogel exhibited electrical conductivity (up to 0.0195 S•cm −1 ). The hydrogel could be used as a strain sensor with a gauge factor of 21.12. The high sensitivity of the hydrogel enabled it to quickly respond to changes in the speed and angle of human joint movements. Therefore, the hydrogel sensor could capture signals from lowamplitude movements such as speaking, smiling, and frowning. The simple preparation strategy for an adhesive, self-healing, frostresistant, and conductive hydrogel reported herein can broaden the range of applications of wearable electronic devices.

show abstract

“…Recently, zwitterionic hydrogel dressings have attracted significant attention and have become competitive candidates for wound management thanks to the ability to have good biocompatibility and antifouling properties (e.g., anti-bacterial adhesion). − Notably, a typical zwitterionic polymer chain with equal anionic and cationic groups (e.g., poly (sulfobetaine methacrylate), PSBMA) exhibits electrically neutral, cationic, and anionic solubilization, producing a hydrated surface layer that can effectively resist the adhesion of biomolecules and microorganisms . Thus, the developed zwitterionic hydrogels have excellent anti-bacterial adhesion properties and can create a wet microenvironment at the wound site, reducing the temperature near the wound and soothing the patient’s pain. , In addition, the zwitterions have strong dipole–dipole interactions with each other, which can be utilized to build self-healing hydrogels and effectively extend the life of the material. − Taking advantage of these unique properties, a growing number of zwitterionic hydrogels are being developed and used to accelerate wound healing. − For example, Zhao and Yuan, developed a zwitterionic hydrogel by one-pot self-initiated polymerization that efficiently promoted angiogenesis in the per wound tissue and accelerated wound healing . Fu and co-workers, developed a mechanically responsive PSBMA hydrogel that can deliver antibiotic drugs under controlled mechanical force, exhibiting excellent antibacterial properties, biocompatibility, and the capacity to cure acute skin wounds in mice .…”

Section: Introductionmentioning

confidence: 99%

Thermoresponsive Self-Healing Zwitterionic Hydrogel as an In Situ Gelling Wound Dressing for Rapid Wound Healing

Wang

Chen

et al. 2022

ACS Appl. Mater. Interfaces

Self Cite

View full text Add to dashboard Cite

It is highly desired yet challenging to fabricate biocompatible injectable self-healing hydrogels with anti-bacterial adhesion properties for complex wounds that can autonomously adapt to different shapes and depths and can promote angiogenesis and dermal collagen synthesis for rapid wound healing. Herein, an injectable zwitterionic hydrogel with excellent self-healing property, good cytocompatibility, and antibacterial adhesion was developed from a thermoresponsive ABA triblock copolymer poly[(N-isopropyl acrylamide)-co-(butyl acrylate)-co-(sulfobetaine methacrylate)]-b-poly(ethylene glycol)-b-poly[(N-isopropyl acrylamide)-co-(butyl acrylate)-co-(sulfobetaine methacrylate)] (PZOPZ). The prepared PZOPZ hydrogel exhibits a distinct thermal-induced sol−gel transition around physiological temperature and could be easily applied in a sol state and in situ gelled to adapt complex wounds of different shapes and depths for complete coverage. Meanwhile, the hydrogel possesses a rapid selfhealing ability and can recover autonomously from damage to maintain structural and functional integrity. In addition, the CCK-8 and 2D/3D cell culture experiments revealed that the PZOPZ hydrogel dressing shows low cytotoxicity to L929 cells and can effectively prevent the adhesion of Staphylococcus aureus and Escherichia coli. In vivo investigations verified that the PZOPZ hydrogel could increase angiogenesis and dermal collagen synthesis and shorten the transition from the inflammatory to the proliferative stage, thereby providing more favorable conditions for faster wound healing. Overall, this work provides a promising strategy to develop injectable zwitterionic hydrogel dressings with multiple functions for clinic wound management.

show abstract

Ultra stretchable, tough, elastic and transparent hydrogel skins integrated with intelligent sensing functions enabled by machine learning algorithms

Cited by 48 publications

References 49 publications

Dual-Stimuli-Responsive and Anti-Freezing Conductive Ionic Hydrogels for Smart Wearable Devices and Optical Display Devices

Dual-Stimuli-Responsive and Anti-Freezing Conductive Ionic Hydrogels for Smart Wearable Devices and Optical Display Devices

Ultra-adhesive Poly(acrylic acid)-Based Hydrogel as a Flexible Sensor for Capturing Human-Motion Signal

Thermoresponsive Self-Healing Zwitterionic Hydrogel as an In Situ Gelling Wound Dressing for Rapid Wound Healing

Contact Info

Product

Resources

About