Ultra-high performance liquid chromatography/time-of-flight mass spectrometry (UHPLC/TOFMS) for time-dependent profiling of raw and steamed Panax notoginseng

Identification and quantification of the anti-inflammatory constituents in Pian-Tze-Huang by liquid chromatography combined with quadrupole time-of-flight and triple quadrupole mass spectrometry

“…The first priority of quality control study is to investigate and confirm their optimal collecting times and sources. Second, some saponin compounds and muscone could be degraded or transformed by the processing time or temperature in the manufacturing process [28,29].…”

Chromatographic separation techniques and data handling methods for herbal fingerprints: A review

“…Numerous linear and non-linear classification techniques exist. The most popular techniques for the classification of herbal products include Linear Discriminant Analysis (LDA) [146,199,[212][213][214], Soft Independent Modelling of Class Analogy (SIMCA) [42,80,195,212,215], Artificial Neural Networks (ANN) [67,216], K-nearest neighbors (k-NN) [67,199,214,217], Partial Least Squares-Discriminant Analysis (PLS-DA) [120,195,199,209,[218][219][220], and Orthogonal Projections to Latent Structures-Discriminant Analysis (OPLS-DA) [218,[221][222][223]. Most techniques have their own strengths and weaknesses.…”

UPLC-Q-TOF-MS E analysis of the constituents of Ding-Zhi-Xiao-Wan, a traditional Chinese antidepressant, in normal and depressive rats

“…Based on a comparison with data in previous studies [9], compounds 10, 50, 92, and 93 were assigned as 20-Glu-Rf, Rg 2 , and ginsenoside Rg 3 or its isomer, respectively. Peaks 11 and 46 generated [M-H] -at m/z 931.5270 and 769.4738, respectively, and were characterised as notoginsenoside R 1 and R 2 [10].…”