Ultra-deep sequencing mutation analysis of the BCR/ABL1 kinase domain in newly diagnosed chronic myeloid leukemia patients

Park, Hyunkyung; Kim, Inho; Kim, Hyeong-Joon; Shin, Dong‐Yeop; Lee, Sung-Yeoun; Kwon, Oh‐Seung; Kim, Dae-Young; Lee, Kyoo‐Hyung; Ahn, Jae‐Sook; Park, Jinny; Sohn, Sang Ho; Lee, Jeong-Ok; Cheong, June Won; Kim, Kyoung Ha; Kim, Hoon-Gu; Kim, Hawk; Lee, Yoo Jin; Nam, Soonkeon; Rok, Young; Park, Sang-Gon; Park, Seong Kyu; Bae, Sung Hwa; Song, Hun Ho; Oh, Doyeun; Jung, Chul Won; Park, Wan Beom

doi:10.1016/j.leukres.2021.106728

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although this technique can detect all mutations spanning the TKD domain, it has lower sensitivity and a longer turnaround time, and is more laborious than other available techniques, such as real-time PCR and droplet digital PCR (dd-PCR). Recently, several studies have demonstrated the application of next-generation sequencing (NGS) techniques, which are superior for the deep molecular early identification and monitoring of single and compound/polyclonal BCR :: ABL1 TKD mutations in CML [48] , [49] , [50] , [51] , [52] , [53] . However, NGS is only available in some laboratories and is difficult to standardize.…”

Section: Introductionmentioning

confidence: 99%