Ulcerogenesis Following Gastric Procedures for Obesity

Marginal ulceration after laparoscopic gastric bypass: an analysis of predisposing factors in 260 patients

“…Helicobacter pylori has been implicated as a possible causative agent in the formation of marginal ulcers after gastric bypass [7]. Findings have shown marginal ulceration to be less common among patients preoperatively screened and treated for H. pylori than among patients who were not screened, and thus not treated [33].…”

An Unusual Complication of Gastric Bypass: Perforated Duodenal Ulcer

“…In recent years, the dominant role of Helicobacter pylori in the etiology of ulcer disease has been recognized, and this organism undoubtedly plays a role in the etiology of these perforations. 6 Of the total 18 cases, free air in the abdominal radiography was only noted in one case. 7 Recognizing that free air under the diaphragm will be absent is one of the most important diagnostic con- siderations when gastric or duodenal ulcer perforation is suspected in the post-gastric bypass patient.…”

H. Pylori as a predictor of marginal ulceration: A nationwide analysis

“…One of the most common complications following RYGB is the development of marginal ulceration and associated symptoms, including epigastric pain, gastric outlet obstruction, upper gastrointestinal bleeding, and gastric perforation. While a variety of risk factors have been implicated in the development of this complication, studies investigating the relationship between H. pylori infection and anastomotic ulcers have yielded conflicting results .…”

“…Helicobacter pylori is known to be a causative factor for gastroduodenal ulceration and is a class I carcinogen for the development of gastric cancer . This organism has also been implicated as a risk factor for marginal ulceration, although studies have yielded conflicting results to date . Furthermore, case reports demonstrate H. pylori has been associated with cancer in the gastric remnant, which is difficult to survey following RYGB .…”