Ulcère de jambe et lymphangite nodulaire à Nocardia brasiliensis en France métropolitaine

Hamm, M.; Friedel, J.; Siré, C.; Semon, J.

doi:10.1016/s0151-9638(05)79419-9

Annales de Dermatologie et de Vénéréologie

2005

DOI: 10.1016/s0151-9638(05)79419-9

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Ulcère de jambe et lymphangite nodulaire à Nocardia brasiliensis en France métropolitaine

M. Hamm¹,

J. Friedel²,

C. Siré³

et al.

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Cited by 3 publications

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“…One may wish to recognise the lymphatic endothelium as putative target for whatever luminal agents or antigens are instigating the Crohn’s disease. Some bacteria are notable for producing lymphangitis, including streptococci,29 corynebacteria,30 pasteurellas31 and nocardia 32 33 . Chlamydia suis when inoculated into weanling pigs produced a transmural enteritis with large lymphohistiocytic aggregates in the submucosa and lymphocytic aggregates that coursed through muscle coats and into the subserosa 34.…”

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confidence: 99%

The forgotten role of lymphangitis in Crohn's disease

Kruiningen

Colombel

2007

Gut

119

108

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Research into Crohn's disease has recently been focused on the genetics of the patient, the gastrointestinal flora, the gut epithelium and mucosal immune responses. For over 60 years pathologists have reported that the fundamental alteration in Crohn's disease occurs in regional lymphatics of the intestine--the disease is a lymphocytic and granulomatous lymphangitis. At an earlier time, experimental sclerosis of regional intestinal lymphatics of the pig produced a chronic segmental enteritis with many features of Crohn's disease, including lymphocytic and granulomatous lymphangitis of the bowel wall and enteroenteric and enterocutaneous fistulas. In Crohn's disease, differences in the anatomic distribution of vasa recta appear to explain long-segment disease of the ileum and short-segment disease of the more proximal intestine. A variety of bacteria and viruses cause lymphangitis, suggesting that microorganisms may be at the centre of the basic changes in Crohn's disease. Dietary antigens and lipids are worthy of consideration as well. Now that antibodies to label lymphatics are available, attention should be directed at defining the initial damage to lymphatic endothelium and agents that might be responsible.

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mentioning

confidence: 99%

The forgotten role of lymphangitis in Crohn's disease

Kruiningen

Colombel

2007

Gut

119

108

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Nocardia brasiliensis in Italy: A nine-year experience

Farina

Andrini²,

Bruno

et al. 2007

Scandinavian Journal of Infectious Diseases

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Primary cutaneous nocardiosis caused by Nocardia takedensis with pulmonary dissemination in an immunosuppressed patient

et al. 2016

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We present a remarkable case of primary cutaneous nocardiosis with pulmonary dissemination due to Nocardia takedensis in a 76-year-old man suffering from marginal zone lymphoma and hypogammaglobulinaemia. We also discuss an alternative treatment to trimethoprim-sulfamethoxazole, which could be contraindicated due to haematological and cutaneous toxicities. This case report is of interest due to the emergence of cutaneous nocardiosis in dermatology.

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Ulcère de jambe et lymphangite nodulaire à Nocardia brasiliensis en France métropolitaine

Cited by 3 publications

References 5 publications

The forgotten role of lymphangitis in Crohn's disease

The forgotten role of lymphangitis in Crohn's disease

Nocardia brasiliensis in Italy: A nine-year experience

Primary cutaneous nocardiosis caused by Nocardia takedensis with pulmonary dissemination in an immunosuppressed patient

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