Ulcerative pigmented squamous cell carcinoma in a 101‐year‐old Japanese woman

Yoshida, Yuichi; Yamasaki, Aigo; Shiomi, Tadahiro; Suyama, Yoshiko; Nakayama, Bin; Yamamoto, Osamu

doi:10.1111/j.1346-8138.2009.00631.x

Cited by 9 publications

(6 citation statements)

References 15 publications

(20 reference statements)

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“…On the basis of our and previous reports, PCSCC should be considered when dealing with a pigmented lesion characterized by an unspecific dermoscopic pattern with the features of diffuse blue-gray pigmentation, scaling, polymorphic vessels and radial structures [1,6,8,9]. …”

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confidence: 99%

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An atypical pigmented lesion on the nose—Answer

Savoia

Gaddoni

Albano

et al. 2019

Dermatol Pract Concept

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confidence: 99%

“…PCSCC is a variant of invasive squamous cell carcinoma, with less than 20 cases reported, to our knowledge, in the English literature [1,2]. PCSCC had been more often reported to occur in the oral mucosa and conjunctiva [3].…”

Section: Answer and Explanationmentioning

confidence: 99%

An atypical pigmented lesion on the nose—Answer

Savoia

Gaddoni

Albano

et al. 2019

Dermatol Pract Concept

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“…A small number of cases (less than 40) of SCC which contain a population of non neoplastic melanocytes, called pigmented SCCs have been reported In the English literature [5,6]. Most of these neoplasms have been described on mucosal surfaces such as the oral and nasal cavity, the conjunctiva [7][8][9][10][11][12][13][14][15][16][17][18] and the uterine cervix [19], as well as on sun-exposed skin such as the head and neck region where 19 cases of pigmented SCC have been described until 2011 [6,[20][21][22][23][24][25][26][27][28][29]. In addition, a case of subungual pigmented SCC has recently been reported [30].…”

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confidence: 99%

Pigmented Squamous Cell Carcinoma of the Lower Back Skin: A Case Report and Review of the Literature

Dimitra¹,

Vassiliki²,

Maria³

et al. 2015

Pigmentary Disorders

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Pigmented squamous cell carcinoma is a rare neoplasm arising mostly in mucous membranes or in sun-exposed skin. We describe a case of this tumor in a 70 year-old man who presented with a pigmented ulcerated nodule on his lower back. Microscopic examination revealed a squamous cell carcinoma (SCC) with atypical proliferation of cells with individual cell keratisation and keratin pearls' formation. Apart from the squamous cell carcinoma a population of cytologically bland dendritic melanocytes was also present, a process that has been described as tumor cell colonization. Differential diagnosis of pigmented SCC includes melanoma with pseudoepitheliomatous hyperplasia, pigmented metatypical basal cell carcinoma and squamomelanocytic tumor, a recently described combined tumor. A small number of cases of pigmented SCC have been referred in the literature mainly located in mucosal surfaces such as the oral and nasal cavity and the conjunctiva but also in sun-exposed cutaneous sites especially at the skin of the head. In the present study, a case of pigmented SCC arising in sun protected skin is described. The authors review the published literature and discuss the histologic differential diagnosis of pigmented SCC as well as the possible mechanisms of melanocytes' colonization in pigmented non-melanocytic malignant neoplasms.

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“…Majority of the studies have found face as the most common site. In 2009, Yoshida et al reported a 2.2x1.5 cm pigmented SCC on the nose of a 101-year-old Japanese woman [6]. In most of the previously reported cases, common age at presentation was old age [7,8].…”

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