Ulcerative cutaneous lesions in the plantar aspect of foot owing to Schizophyllum commune

Abstract

Schizophyllum commune is an emerging basidiomycetous fungus increasingly reported attributing pulmonary infections. However, the involvement of S. commune in primary cutaneous ulcerative lesions in humans has not yet been reported. The aetiology of S. commune in wound infection may be overlooked or misdiagnosed. This may be due to the atypical colony morphology, lack of sporulation, and familiarity with this fungus as well as the difficulty in accurate identification. We report here the first case of an ulcerative cutaneous infection caused by S. commune in the plantar aspect of foot in a healthy individual. Skin grafting was performed and the wound healed completely.

Pulmonary infection of Schizophyllum commune diagnosed by metagenomic next- generation sequencing: A case report

“…Literature reports on Schizophyllum commune have mostly implicated the fungus with pulmonary manifestations ranging from sinusitis, allergic bronchopulmonary mycoses, brochial mucoid impaction, pulmonary fungal balls, asthma, chronic eosinophilic pneumonia, brochogenous cysts, and so on. [4] Pulmonary imaging and clinical laboratory examination usually lack specificity. According to the vitro post infection experiment of mice, [5] the mycology and laboratory research progress of Schizophyllum commune speculated that the pathogenesis may induce serious local inflammatory reaction and produces inflammatory suppurative granulomatous lesions and fibrosis.…”