2014
DOI: 10.1136/archdischild-2013-305512
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Ulcerative colitis: management in adults, children and young people (NICE Clinical Guideline CG166)

Abstract: The National Institute for Health and Care Excellence (NICE) published a clinical guideline in 2013 entitled 'Ulcerative colitis: Management in adults, children and young people (NICE Clinical Guideline CG166)'. This guideline review discusses the evidence base, compares the guideline with current practice and published guidelines, and summarises the key points relevant to pediatricians who manage children with UC.

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Cited by 18 publications
(15 citation statements)
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“…Both are life long, relapsing disorders of unknown etiology; possibly the result of interaction between genetic and environmental factors[1]. The diagnosis of these disorders is based on clinical features, endoscopy, and histological changes[2].…”
Section: Introductionmentioning
confidence: 99%
“…Both are life long, relapsing disorders of unknown etiology; possibly the result of interaction between genetic and environmental factors[1]. The diagnosis of these disorders is based on clinical features, endoscopy, and histological changes[2].…”
Section: Introductionmentioning
confidence: 99%
“…The presentation includes bloody diarrhea, rectal urgency and abdominal cramping. Conventional therapy based on corticosteroids, salicylates (sulfasalazine, 5‐aminosalicylic acid) or immunosuppressive agents is commonly used for induction and maintenance of remission . The aim is to reduce the production or action of inflammatory mediators.…”
Section: What Is Known and Objectivementioning
confidence: 99%
“…3 Furthermore, UC occurs most commonly between the ages of 15 and 25. 4 However, medical cures for UC have yet to be established, despite a long history of clinical research. Thus, after the onset of UC at young ages, patients require long-term followup colonoscopy observations to maintain their QOL.…”
Section: Introductionmentioning
confidence: 99%