Ulcerative Colitis in Children 10 Years Old or Younger

Inflammatory bowel disease in children: epidemiological analysis of the nationwide IBD registry in Japan

“…In a small series of pediatric UC patients reported by Gryboski et al [33], 11% had severe, 37% moderate and 53% mild disease. In 171 patients reported by Hyams et al [34], 57% had moderate or severe, and 43% had moderate disease.…”

Children with early-onset inflammatory bowel disease (IBD): Analysis of a pediatric IBD consortium registry

“…[17][18][19][20][21] In contrast, in North America, most available information originates primarily from single-center studies. 16,[22][23][24][25][26] In addition, the characteristic features of early-onset IBD (ie, #6 years old) and its natural history have only recently been reported in small case series. 3,23 Previous studies in the United States and Canada have used local hospital registries to examine features and complications of pediatric IBD, including extraintestinal manifestations of IBD, perianal disease, and outcomes of medical and surgical therapies.…”

Inflammatory bowel disease in children and adolescents in Italy: Data from the pediatric national IBD register (1996–2003)

“…It is estimated that 20%–30% of patients experience onset of their symptoms under 20 years of age 1–4. There are literature reports of cases where the diseases began before 1 year of age 5, 6. The pathogenesis of IBD is still unknown; environmental, genetic, and immunological factors seem to play an important role 7–11…”