Ulcerative Colitis after Multidisciplinary Treatment for Colorectal Cancer with Multiple Liver Metastases: A Case Report

Abstract

: Herein we report on an extremely rare case of ulcerative colitis UC with onset after chemotherapy and colorectal resection, and discuss three previously reported cases. A 61-year-old man presented with fecal occult blood and no subjective symptoms. The diagnosis was rectal cancer with multiple liver metastases. Following chemotherapy, the patient underwent laparoscopy-assisted super-low anterior resection, liver resection. On Day 35 following closure of the ileostomy, the patient was referred to Totsuka Kyoritsu Dai-1 Hospital because of diarrhea, bloody stools. Colonoscopy and pathological examination revealed UC. To the best of our knowledge, only three cases of UC following colorectal cancer resection have been described previously. In conclusion, when encountering intractable diarrhea after chemotherapy or surgery, UC should be one of the bowel diseases considered, with prompt systemic examination recommended.

Total proctocolectomy with end ileostomy for acute onset of ulcerative colitis during chemoradiotherapy for lung adenocarcinoma (successfully treated by surgery): a case report

“…Tomioka et al reported a case of UC after chemotherapy and colorectal resection. The authors considered that four factors including chemotherapy, colorectal operative stress, changes in blood circulation because of surgery, and mental stress are responsible for the onset of UC [13].…”