Ulcerated lobular panniculitis: An unusual initial presentation of anti-Mi-2-alpha positive dermatomyositis

Ambooken, Betsy; Balakrishnan, Pravitha Pookkottil; Asokan, Neelakandhan; Krishnan, Jijith

doi:10.25259/ijdvl_848_2021

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Among these paediatric common RID, MPI has been reported to occur both endemically and epidemically worldwide with a higher prevalence in certain seasons as autumn and winter [ 29 ] and has been associated with a wide range of clinical manifestations, including pneumoniae, upper respiratory tract infection, and tracheobronchitis. Of note, rare cases of cavitary lung lesions and mucositis also show the diverse impact of MPI on human health [ 30 ]. These recent updates highlighted the ongoing significance of MPI as a global health concern and the importance of continued surveillance and research.…”

Section: Discussionmentioning

confidence: 99%

Epidemic features and megagenomic analysis of childhood Mycoplasma pneumoniae post COVID-19 pandemic: a 6-year study in southern China

Xu,

Yang,

Sun

et al. 2024

Emerging Microbes & Infections

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With the atypical rise of Mycoplasma pneumoniae infection (MPI) in 2023, prompt studies are needed to determine the current epidemic features and risk factors with emerging trends of MPI to furnish a framework for subsequent investigations. This multicentre, retrospective study was designed to analyse the epidemic patterns of MPI before and after the COVID-19 pandemic, as well as genotypes and the macrolide-resistance-associated mutations in MP sampled from paediatric patients in Southern China. Clinical data was collected from 1,33,674 patients admitted into investigational hospitals from 1 June 2017 to 30 November 2023. Metagenomic next-generation sequencing (mNGS) data were retrieved based on MP sequence positive samples from 299 paediatric patients for macrolide-resistance-associated mutations analysis. Pearson's chi-squared test was used to compare categorical variables between different time frames. The monthly average cases of paediatric common respiratory infection diseases increased without enhanced public health measures after the pandemic, especially for influenza, respiratory syncytial virus infection, and MPI. The contribution of MPI to pneumoniae was similar to that in the outbreak in 2019. Compared to mNGS data between 2019–2022 and 2023, the severity of MP did not grow stronger despite higher rates of macrolide-resistance hypervariable sites, including loci 2063 and 2064, were detected in childhood MP samples of 2023. Our findings indicated that ongoing surveillance is necessary to understand the impact of post pandemic on MP transmission disruption during epidemic season and the severity of clinical outcomes in different scenarios.

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Section: Discussionmentioning

confidence: 99%

Epidemic features and megagenomic analysis of childhood Mycoplasma pneumoniae post COVID-19 pandemic: a 6-year study in southern China

Xu,

Yang,

Sun

et al. 2024

Emerging Microbes & Infections

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Oral findings as a clinical tool to differentiate between lupus erythematosus and dermatomyositis patients

Robles-Silva

Barrio‐Díaz

Reyes-Vivanco

et al. 2023

Preprint

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Background Dermatomyositis (DM) patients are frequently misdiagnosed as having lupus erythematosus. There are few tools to differentiate between these diseases.Objective To compare oral findings between patients with systemic lupus erythematosus (SLE), cutaneous lupus erythematosus (CLE), and DM patients to explore new clinical tools that allow differentiating between these conditions.Methods We conducted an observational, transversal, and analytical study between 2016 and 2021. One hundred sixty-seven patients were included (77 SLE, 56 CLE, and 34 DM). All patients who presented with more than one of these diseases simultaneously were excluded. All patients had a clinical evaluation of the oral cavity. We obtained photographs of the tongue, hard and soft palate, upper and lower gingiva, and jugal mucosa. Three dermatologists, blinded to the diagnosis of the diseases studied, registered the presence of the lesions of interest.Results The presence of brown pigmentation in the gingiva, whitish streaks in the jugal mucosa, palatal cobblestones, and gingival cobblestones were associated with SLE and CLE when compared with DM patients. Palatal cobblestones were present exclusively in patients with SLE and CLE. Gingival telangiectasias were associated with DM when compared with SLE, and palatal telangiectasias and well-defined palatal lesions were associated with DM when compared with SLE and CLE. Most DM patients presented palatal telangiectasias (94.12%), while this finding in SLE and CLE patients was infrequent (7.79% and 5.36%, respectively).Conclusion Oral findings can help differentiate between SLE, CLE, and DM patients when there is a diagnostic dilemma between these conditions.

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Ulcerated lobular panniculitis: An unusual initial presentation of anti-Mi-2-alpha positive dermatomyositis

Cited by 2 publications

References 9 publications

Epidemic features and megagenomic analysis of childhood Mycoplasma pneumoniae post COVID-19 pandemic: a 6-year study in southern China

Epidemic features and megagenomic analysis of childhood Mycoplasma pneumoniae post COVID-19 pandemic: a 6-year study in southern China

Oral findings as a clinical tool to differentiate between lupus erythematosus and dermatomyositis patients

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