Uji Stabilitas Fisik Sediaan Masker Gel dari Ekstrak Alga Merah (Poryphyra sp)

Numberi, Aurina Megawati

doi:10.24198/mfarmasetika.v5i1.24066

Cited by 8 publications

(5 citation statements)

References 5 publications

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“…Changes in the pH value that occur during storage indicate a reaction in the components that make up the preparation so that it can increase or decrease pH 32 . According to Numberi et al 33 , changes in pH during storage indicate a less stable preparation. Changes in pH value are influenced by sorbitol, with an acidity level of 4.5 34 .…”

Section: Ph Testmentioning

confidence: 99%

Nanoemulsion Mouthwash Formulation of Bajakah Tampala (Spatholobus littoralis Hassk.) Skin Extract Against Candida albicans

Hamzah,

Gunawan,

Pratiwi

et al. 2024

Borneo J Pharm

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Candida albicans can cause two infections in humans: superficial and systemic. The ability of C. albicans to infect the host is influenced by virulence factors and character changes so that it can fool the immune system. From the character change factor, C. albicans can form a biofilm. This study aims to determine the good concentration in inhibiting and determine the antifungal and antibiofilm activity of nanoemulsion mouthwash formulation of bajakah tampala (Spatholobus littoralis Hassk) skin extract against C. albicans. This research was conducted with an experimental method. The formulation used a spontaneous magnetic stirrer technique to make nanoemulsion preparations. Antifungal and antibiofilm tests were carried out by dilution method using a 96-well plate and a microplate reader with a wavelength of 620 nm to determine the percentage inhibition against C. albicans and determine MIC50 and MBIC50. The results showed that the nanoemulsion mouthwash formulation of S. littoralis inhibited the planktonic and biofilm of C. albicans. The concentration of 1% is expressed as MIC50 and MBIC50. Therefore, the nanoemulsion formulation of S. littoralis extract could inhibit the growth of C. albicans in the oral cavity.

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Section: Ph Testmentioning

confidence: 99%

Nanoemulsion Mouthwash Formulation of Bajakah Tampala (Spatholobus littoralis Hassk.) Skin Extract Against Candida albicans

Hamzah,

Gunawan,

Pratiwi

et al. 2024

Borneo J Pharm

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“…Filter again after 3 days to get a liquid extract. The two liquid extracts were concentrated using a rotary evaporator at 40°C to produce a thick extract (Numberi, 2020).…”

Section: ) Extraction Of Red Algaementioning

confidence: 99%

FORMULATION AND ACTIVITY TESTING OF RED ALGAE (Eucheuma cottonii) EXTRACT GEL AGAINST THE BACTERIA Propionibacterium acnes

Awaluddin,

Thayeb,

Utari

et al. 2023

jppipa, pendidikan ipa, fisika, biologi, kimia

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Flavanoids are one of the many compounds in phenols that have the ability to denature bacterial cell membrane proteins, thus inhibiting cell growth. The purpose of this study was to formulate an anti-acne gel for the ethanolic extract of red algae (Eucheuma cottonii) and to test its antimicrobial activity against Propionibactericum acnes. The method used is laboratory research design by making antiacne gel preparations of red algae extract with concentrations of 1%, 3%, 5% and testing the antimicrobial activity with the agar diffusion method using wells on MHA media which is incubated for 1x24 hours. The results of the evaluation of the gel preparation before and after the cycling test met the requirements of organoleptic, homogeneity, pH, viscosity, and dispersibility where each formula was stable in the gel preparation. The results showed that red algae extract (Eucheuma cottonii) could be formulated and was stable in the form of an anti-acne gel and had antibacterial activity. In formula I with a concentration of 1% the inhibition zone formed was 36.33 mm, in formula II with a concentration of 3% the inhibition zone formed was 38.79 mm and in formula III with a concentration of 5% the inhibition zone formed was 34.27 mm. So that which has optimal antibacterial activity against Propionibacterium acnes is formula II with a concentration of 3% and an area of inhibition zone of 38.79 mm

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“…Pengujian ini dilakukan dengan cara mengoleskan sediaan dari lulur bayam merah pada bagian lengan bawah atau dibelakang daun telinga terhadap 15 orang sukarelawan, dibiarkan terbuka dan diamat. Adapun pengamatan yang dilakukan untuk uji ini antara lain reaksi iritasi positif ditandai oleh adanya kemerahan, gatal-gatal, ruam atau bengkak pada kulit telinga yang diberi perlakuan [32,33].…”

Section: Uji Iritasiunclassified

Uji Sifat Fisik Sediaan Lulur Ekstrak Bayam Merah (Amaranthus tricolor L.) Serta Uji Efektivitas Kelembaban (Moisture) Dan Kehalusan (Evenness) Pada Kulit

Iskandar,

Tarigan,

Leny

et al. 2023

Maj. Farmasetika

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Sediaan lulur atau“body scrub” merupakan salah satu dari banyaknya sediaan kosmetik, lulur tersendiri berfungsi membuang ataupun mengangkat sel mati. Bayam merah (Amaranthus tricolor L.) adalah tanaman ataupun lebih tepatnya jenis sayuran yang biasa dikonsumsi sehari-hari yang bisa dimanfaatkan sebagai bahan baku dari sediaan lulur karena tingginya kandungan antosianin. Antosianin pada bayam merah bermanfaat sebagai antioksidan yang mampu menghambat radikal bebas. Bayam merah juga kaya akan kandungan vitamin A, Vitamin C, protein, kalsium, dan lainnya. Adapun tujuan dari studi ini adalah untuk mengetahui bayam merah yang dapat diformulasikan menjadi sediaan lulur atau body scrub yang memiliki karakteristik yang stabil dan mampu memperbaiki, meningkatkan kadar air pada kulit serta kehalusan pada kulit. Proses dan metode studi ini dengan mengekstraksi daun bayam merah (Amaranthus tricolor L.) dengan maserasi, kemudian formulasi sediaan lulur dibuat dengan beberapa variasi konsentrasi yaitu 0,5%, 1% dan 1,5%. Pengujian sediaan meliputi organoleptis, homogenitas, pH, daya sebar, iritasi, uji stabilitas, uji efektivitas kelembaban dan kehalusan dengan menggunakan instrumen skin analyzer pada kulit sukarelawan. Hasil studi yang dibuktikan dengan membandingkan hasil sebelum dan setelah cycling test menunjukan bahwa sedian lulur dari masing-masing formula memenuhi persyaratan organoleptis, homogenitas, pH lulur 5,7-5,9 (persyaratan pH sediaan ke kulit yaitu 4,5-6,5), daya sebar 5,3-5,6 (persyaratan 5-7 cm), tidak mengiritasi kulit, serta uji efektivitas kelembaban (moisture) dan kehalusan (evenness) pada kulit sukarelawan menunjukkan hasil analisis studi yang signifikan (p ≤ 0,05) pada F1, F2, F3 dan tidak menunjukkan hasil analisis yang signifikan (p ≥ 0,05) pada F0. Kesimpulan yang dapat diambil dari studi ini bahwa ekstrak daun bayam merah (Amaranthus tricolor L.) dapat diformulasikan serta memenuhi persyaratan uji sifat fisik sediaan lulur atau body scrub, tidak menyebabkan iritasi pada kulit, serta dapat memberikan kenaikan nilai persentase efek yang melembabkan kulit dan menghaluskan kulit dengan menggunakan skin analyzer.

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Uji Stabilitas Fisik Sediaan Masker Gel dari Ekstrak Alga Merah (Poryphyra sp)

Cited by 8 publications

References 5 publications

Nanoemulsion Mouthwash Formulation of Bajakah Tampala (Spatholobus littoralis Hassk.) Skin Extract Against Candida albicans

Nanoemulsion Mouthwash Formulation of Bajakah Tampala (Spatholobus littoralis Hassk.) Skin Extract Against Candida albicans

FORMULATION AND ACTIVITY TESTING OF RED ALGAE (Eucheuma cottonii) EXTRACT GEL AGAINST THE BACTERIA Propionibacterium acnes

Uji Sifat Fisik Sediaan Lulur Ekstrak Bayam Merah (Amaranthus tricolor L.) Serta Uji Efektivitas Kelembaban (Moisture) Dan Kehalusan (Evenness) Pada Kulit

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