Uji Aktivitas Sediaan Sampo Antiketombe Ekstrak Daun Ketepeng Cina (Cassia alata L) Terhadap Jamur Pityrosporum ovale

Abstract

Dandruff is a health problem that is often experienced by most people because it can reduce self-confidence. The aim of this research is to determine the extract of Chinese ketepeng leaves (Cassia alata L) as an anti-dandruff shampoo preparation and to determine the activity of the shampoo against Pityrosporum ovale and Candida albicans fungi using laboratory experimental methods. This research is divided into three concentration variations, namely 10% - 15% 20% and two supporting controls, namely control (-) without extract and control (+), namely ketomed shampoo. Results: The results of the research for the inhibitory power of the fungus Pityrosporum ovale without extract (-) have a value of 4.43 mm at a concentration of 10% have an inhibition zone of 17.23 mm at a concentration of 15% have an inhibitory zone value of 18.67 mm at a concentration of 20% have the value of the inhibition zone is 19.66 mm in the control (+) which has a value of 20.87 mm. In Candida albicans without extract (-) it has a value of 2.33 mm at a concentration of 10% it has an inhibition zone value of 16.44 mm at a concentration of 15% it has an inhibition zone value of 17.76 mm at a concentration of 20% it has an inhibition zone value of 19.37 mm at control (+) has a value of 20.54 mm. Chinese ketepeng (Cassia alata L.) leaf extract can be used as an anti-dandruff shampoo, based on the results of the preparation evaluation it was found that the formula with a concentration of 15% meets the characteristics of a good shampoo, and the flavonoid compound content in Chinese Ketapang (Cassia alata L.) leaf extract is 15% has a high zone of inhibition against P. ovale and C. albicans fungi. So it can be concluded that the best formula obtained in this study was at an extract concentration of 15%.