Ueber eine eigenartige Form von „Atrophia maculosa cutis”

Jadassohn,

doi:10.1007/bf01940211

Cited by 37 publications

(8 citation statements)

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“…They described multiple sac‐like tumors on the upper back, chest, shoulders and arms, which depressed upon palpation and similar to a ventral hernia, protruded upon release . In 1892, Jadassohn reported the first case of ‘inflammatory’ anetoderma in a 23‐year‐old female with depressed pink to red lesions with an atrophic, wrinkled appearance located on her elbow . Historically, anetoderma is clinically classified as inflammatory, the Jadassohn–Pellizzari type, or non‐inflammatory, the Schweninger–Buzzi type; however, both types can coexist in the same patient and are pathologically identical …”

Section: Discussionmentioning

confidence: 99%

Anetoderma arising in Reed syndrome: a case report and review of the literature

2015

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Anetoderma is a cutaneous disorder characterized by loss of dermal elastic tissue resulting in papules from herniation of subcutaneous tissue or circumscribed areas of atrophic, wrinkled skin. Familial leiomyomatosis cutis et uteri (Reed syndrome) is an autosomal dominant disorder characterized by cutaneous and uterine leiomyomas. We report a 23-year-old male with Reed syndrome who presented with asymptomatic pearly white, atrophic, flaccid papules on the upper back and shoulder that depressed when palpated. Pathologic examination showed an unremarkable epidermis and central loss of dermal elastin, bordered by clumped elastin, as revealed with an elastin stain. The correlation of clinical and pathologic findings indicated a diagnosis of anetoderma arising in a patient with Reed syndrome.

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Section: Discussionmentioning

confidence: 99%

Anetoderma arising in Reed syndrome: a case report and review of the literature

2015

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“…Anetoderma presents clinically as circumscribed, hypopigmented atrophic macules which are usually localized to the trunk and upper extremities. 22 Sometimes it also presents as atrophic patches. 'Herniation phenomenon' during palpation is a helpful sign in clinical evaluation of anetoderma.…”

Section: Upper Dermis Affectedmentioning

confidence: 99%

The utility of elastic Verhoeff‐Van Gieson staining in dermatopathology

et al. 2012

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Elastic fibers are important components of the skin and are responsible for skin elasticity. Genetic defects are well-known in numerous hereditary elastic tissue disorders and skin biopsies are often the first step in the evaluation of those disorders. Verhoeff-Van Gieson elastic staining is a simple method that is used for visualizing elastic fibers. With the development of modern immunohistochemical methods, the value of routine histochemical staining is sometimes underestimated. Histochemical stains are less expensive, easy to perform and help to resolve numerous diagnostic quandaries in dermatopathology. This article focuses on the value of elastic tissue staining in dermatopathology, with a focus on primary elastic tissue disorders, alopecia, inflammatory skin disorders and neoplastic proliferations. Connective tissue comprises of three types of fibers: collagen fibers, reticular fibers and elastic fibers. These fibers are made of proteins and composed of long peptide chains. While the main function of collagen and reticular fibers is to provide tensile strength and support respectively, the elastic fibers are mainly there for providing stretchability and flexibility. Elastic fibers can stretch up to 1.5 times their length, and snap back to their original length when relaxed. The long and branching arrangement of fibers enables them to stretch and recoil thus providing flexibility to tissues. Elastic fibers are composed of two structural components: elastin and microfibrils, and include elastin, elaunin and oxytalan.

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“…The term "anetodermia" was first reported by Schweninger and Buzzi in 1891, 2 and again by Jadassohn in 1892. 3 Since then, many cases of anetoderma have been reported under different terms. The term "macular atrophy" has been mainly used because of the clinical features, while it could be confusing because the term has also been used in other conditions showing dermal atrophies.…”

Section: Discussionmentioning

confidence: 99%

Japanese familial anetoderma: A report of two cases and review of the published work

Fukayama

Miyagaki

Akamata

et al. 2018

The Journal of Dermatology

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Anetoderma is a rare cutaneous disorder characterized by focal loss of dermal elastic tissue, resulting in macular atrophy or herniated saclike skin. Some families with hereditary anetoderma have been described, but there have been no reports on Japanese familial anetoderma so far. We herein report two Japanese sibling cases of primary anetoderma. A healthy 13‐year‐old Japanese girl and a healthy 15‐year‐old Japanese girl presented to our hospital with a 6‐month history of small atrophic pittings on their arms and trunks. All lesions were less than 0.5 cm in diameter, which are relatively small for non‐familial anetoderma. Preceding infections or skin lesions were not observed. A skin biopsy revealed a focal, complete loss of elastic tissue in the superficial to mid‐dermis which was surrounded by fine, irregular or twisted elastic fibers. Based on these findings, the diagnosis of anetoderma was made. Review of published works demonstrated that the mode of inheritance of familial anetoderma is not simple, suggesting that it is important to survey any family member of the patients with anetoderma.

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Ueber eine eigenartige Form von „Atrophia maculosa cutis”

Cited by 37 publications

References 0 publications

Anetoderma arising in Reed syndrome: a case report and review of the literature

Anetoderma arising in Reed syndrome: a case report and review of the literature

The utility of elastic Verhoeff‐Van Gieson staining in dermatopathology

Japanese familial anetoderma: A report of two cases and review of the published work

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