“…Krogh's doubts (7) as to the usefulness of attempting to get a real basal figure on the score that the functional activities of the various organs are responsible for a considerable part of the metabolism, and that only by stopping these, including presumably the heart, could a theoretical basal be obtained, seem countered by the fact that (a) a fairly constant figure can be obtained after four or five days' fasting, and (b) if functional activity of all organs be excluded we can hardly be considered to be dealing with a living animal. It is just possible that observations taken in the morning at about nine or ten o'clock, after say 17 hours' fasting, might be steady for a couple of hours or so, owing to interruption of the fall by superposition of some diurnal rhythm of metabolism with a maximum in the forenoon, of the existence of which we have a certain amount of evidence, so far unpublished, and which was noted by Johansson (8) in men, and ascribed to the influence of daylight, noise and psychic tone (psychischen Thatigkeitzustand). It is however difficult to see what theoretical value could be ascribed to such a figure.…”