Abstract:Poster Sessions C787 not resemble any known structure. SsAPRTase is to our knowledge the fi rst archaean APRTase to be structurally characterized.We will present dimeric P6 1 structures of "apo" SsAPRTase (with PO 4 3-) together with the complexes SsAPRTase:AMP (product) and SsAPRTase:ADP (inhibitor) based on ESRF (Grenoble) synchrotron data to about 2.4 Å resolution. The current work concentrates on obtaining substrate complexes of SsAPRTase. Glycosyltransferases (GTs) are carbohydrate-active enzymes with ess… Show more
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