Über thalamische Demenz

Grünthal, E.

doi:10.1159/000148462

Cited by 31 publications

(5 citation statements)

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“…The important role in the pathogenesis of dementia played by the central area of the dominant hemisphere was previously noted by Dandy (36) and Alford (37). Moreover, there have been several descriptions of special types of infarctions that were probably causative of dementia, e.g., infarction of the association field of the frontal lobes (38), infarctions of the bilateral hippocampi or temporal lobes (39, 40), infarction of the left hippocampus (41), infarctions of the basal regions of the bilateral occipital lobes (amnésie des occipitaux) (42), thalamic infarction (43), watershed infarction associated with unilateral or bilateral obstruction of the internal carotid arteries (44), a lacunar state in the bilateral central regions (45), and lacunar infarctions of the bilateral internal capsules (46). Thus it seems reasonable to take the location as well as the quantity into consideration in defining the extent of vascular lesions causing dementia.…”

Section: Discussionmentioning

confidence: 99%

Senile Degenerative Brain Lesions and Dementia

Morimatsu

Hirai

Muramatsu

et al. 1975

J American Geriatrics Society

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In a study of senile degenerative lesions-including Alzheimer's neurofibrillary changes, senile plaques and amyloid angiopathy-the hippocampal area of the brain was examined by thioflavine T fluorescence microscopy in 146 consecutive autopsy patients over the age of 49. The incidence and quantity of neurofibrillary changes and senile plaques rose with age, and an approximate positive correlation in quantity was noted among the three kinds of degenerative change. The quantity of neurofibrillary lesions and senile plaques was significantly different between the demented and non-demented patients, but not between the severely and less severly demented patients. The cause of dementia was studied retrospectively, based on the extent of morphologic changes in the brain, thus classifying dementia into three types: degenerative, vascular, and mixed. Clinically, the mixed type resembled the vascular type with regard to major neurologic signs, and there was some similarity to the degenerative type with regard to mental features.

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Section: Discussionmentioning

confidence: 99%

Senile Degenerative Brain Lesions and Dementia

Morimatsu

Hirai

Muramatsu

et al. 1975

J American Geriatrics Society

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“…This finding was compatible with thalamic infarction, and involved the dorsomedial, intralaminar and ventrolateral nuclei. It is well knownthat bilateral thalamic lesions cause memoryimpairment (1). Recently, some cases with amnestic syndrome due to unilateral thalamic lesion have been reported (2)(3)(4)(5)(6)(7)(8)(9).…”

Section: Discussionmentioning

confidence: 99%

“…It is well knownthat bilateral thalamic lesions cause memory impairment (1) and some cases with amnestic syndromedue to unilateral thalamic lesion have been reported (2)(3)(4)(5)(6)(7)(8)(9). Recently, Baron et al (10) suggested from their study by positron emission tomography (PET) that unilateral thalamic lesion causes ipsilateral cortical hypometabolism and that this cortical hypometabolism and neuropsychological deficit, including memory impairment, are related causally.…”

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confidence: 99%

A case of amnestic syndrome due to right thalamic infarction.

et al. 1990

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A 66-year-old right-handed womanwith amnestic syndrome due to right thalamic infarction, is described. Amnestic syndrome in this case was both anterograde verbal and non-verbal (visuospatial) memoryimpairment in the acute stage and only non-verbal impairmentin the chronic stage. On the basis of these observations and previous reports, it was concluded that her memoryimpairment may be the result of cortical hypometabolism following thalamic infarction.

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“…So erlaubt uns der Nachweis kleiner doppelseitiger Thalamus• läsionen verschiedene Syndrome "in vivo" zu diagnostizieren, die yor der Ära der Computertomographie erst nach einer feingeweblichen Untersuchung des Gehirns erkannt werden konnten. Seit langem schon ist bekannt, daß der doppelseitige Untergang bestimmter Thalamuskerne ein dementielles Syndrom vcerursachen kann, für das GrünthaI (1942) folgerichtig den Begriff "thalamische Demenz" geprägt hat.…”

Section: Zusammenfassungunclassified