Über Porphyrine und ihre Synthesen

The Metabolism of Blood Pigments in Pernicious Anemia

“…This would make understandable a natural synthesis which is similar in general to the one which he developed in the laboratory (10).…”

“…In this way an index of the rate of marrow activity has been correlated with an index of the rate of destruction of erythrocytes. For an understanding of the rationale of this procedure a brief review of the metabolism of the porphyrins is required (7,8,9,10). 1 Porphyrins are substances which contain a porphin nucleus composed of four pyrrol nuclei united by four methene groups.…”