“…In 1929 Is reported a study of over 100 children with perlèche, all from the same institution, in 77 per cent of whom fungi imperfecti, Monilia chiefly, were isolated from the lesions, with cultures of which the disease was reproduced in children from the same institution, chil¬ dren who presented grossly normal oral commissures, and the organisms were recovered in pure culture from the experimentally produced lesions. Similar findings have been recorded, chiefly in adults, by Robinson and Moss," Skolnik, 10 Freund,11 Frank,12 McLeod ls and a number of other investigators. MALOCCLUSION …”