Über die Verwendung der Barbitursäure für die photometrische Bestimmung von Cyanid und Rhodanid

Novel Sensitive Spectrophotometric Method for the Trace Determination of Cyanide in Industrial Effluent

“…4 Spectrophotometric methods [6][7][8] for the determination of cyanide are far more superior to the other methods, such as titrimetric, 9 polarographic, 10 fluorometric 11 and chromatographic techniques. 12 A trace amount of cyanide is often determined by spectrophotometry by the pyridine-benzidine method of Aldridge, 6 the pyridine-pyrazolone method of Epstein, 7 the pyridine-barbituric acid method of Asmus and Garschagen 13 and the pyridine-p-phenylenediamine method of Bark and Higson. 8 However, these methods have certain drawbacks, such as the carcinogenic properties of benzidine, the instability of the pyridine-pyrazolone reagent, the slow color development in the pyridine-p-phenylenediamine method and the rapid fading of color in the pyridine-barbituric acid method.…”

Self-Administration of Pralidoxime in Nerve Gas Poisoning with A Note on the Stability of the Drug

“…Hydroxylamine and hydrogen cyanide are initially formed during breakdown of P2S (Creasy and Green, 1959;Ellin and Kondritzer, 1959). Hydroxylamine was determined colorimetrically with a diazo reaction after conversion to nitrite (Csaky, 1948) and hydrogen cyanide with a modified Zincke-Konig reaction (Asmus and Garschagen, 1953). To be able to determine eventual hydrogen cyanide, the ampoules used were broken in a plastic test-tube together with N sulphuric acid.…”

“…The possibihty of administering the drugs by automatic injectors has been discussed (Barkman, 1960), but insufficient information has been available concerning the practicability of this proposition. It is not known if it is possible, with an automatic injector, to administer the relatively large doses that generally have been considered necessary for a reliable therapeutic effect.…”

An Improved Method for Determination of Thiocyanate in Plasma and Urine

“…In the K nig method (9) the cyanogen halide then reacts with pyridine yielding glutaconic aldehyde, and this compound then reacts with a primary amine producing a dye which is quantified spectrophotometrically. After the first description of the method several modifications have appeared (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26), but unfortunately all of them involve handling of unpleasant or toxic compounds, e. g. bromine, arsenite, benzidine, pyridine and l-phenyl-3-methyl-5-pyrazolone.…”