Über die nur mikroskopisch erkennbare Form der Periarteriitis nodosa

Abstract

Trotzdem seit Erscheinen des bekannten Sammelreferats yon Gruber fiber die Periarteriitis nodosa (P. n.)

Advances in the Treatments of Systemic Vasculitides

“…Although the designation microscopic PAN appeared relatively early in the medical literature [3], that particular form of systemic vasculitis was individualized by Davson et al [4] only in sensus conference [2].…”

Microscopic Polyangiitis: from Pathogenesis to Treatment

“…The term polyarterites nodosa (PN) was introduced to describe all the patients with non infectious arteritis [1]. In 1923, a new distinct entity from PN was described the so-called ''microscopic form of periarteritis nodosa'' characterized both by the presence of glomerulonephritis and non granulomatous inflammation [7]. Later, a stretch correlation of ''microscopic form of periarteritis nodosa'' with Wegener's granulomatosis and Churg-Strauss syndrome now called granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis was described respectively [8].…”

“…Use of plasma infusion is limited to patients with relapse or to those resistant to immunosuppression treatment [7]. The long term effect of plasmapheresis on patients' outcome is unknown.…”

Historical stages of the study of systemic necrotizing vasculitides

“…Термин «микроскопический узелковый периартери-ит» первым использовал в 1923 г. немецкий невропатолог Фридрих Волвил (Friedrich Wohlwill) из Гамбурга при опи-сании двух пациентов, которые погибли от заболевания, протекавшего с миалгиями, парезом и ГН [23]. При гисто-логическом исследовании был обнаружен трансмуральный артериит без образования аневризм, характерных для клас-сического УП, а также воспаление венозного русла, что, по современным представлениям, в первую очередь свой-ственно МПА, а не УП.…”