IntroductionThe clinical diagnosis of Wallenberg's syndrome is based on classical features such as loss of pain and temperature sensation on the ipsilateral face and contralateral body and limbs, ipsilateral Horner's sign, dysphagia, dysphonia, gait ataxia, and nystagmus [26]. The variability of the clinical pattern, however, is much greater than was initially described [4,14,21] due to the variable arterial supply of the affected region [6,7].We investigated laser-evoked (LEP) and electrically evoked somatosensory (SSEP) potentials, magnetically evoked potentials (MEP), and the blink reflex and examined the correlation between lesion topography and brainstem function in two patients with dissociated hemianalgesia and a sensory level on the contralateral side due to ventrolateral medullary infarction.
Material and methodsLaser-evoked potentials Painful stimuli were generated by an infrared thulium laser (wavelength = 2.01 µm, energy 540 mJ for the hand and 600 mJ for the foot; duration 3 ms; diameter 5 mm beam). Perception and pain thresholds were determined by the method of limits using three ascending and descending energy series. LEP after stimulation of two skin Abstract We investigated two patients presenting with the rare finding of almost isolated hemianalgesia with a sensory level on the contralateral side sparing the face. Clinical findings, electrophysiological studies (absent laser-evoked pain-related somatosensory potentials, normal electrically evoked somatosensory potentials, magnetically evoked potentials, and blink reflexes), and magnetic resonance imaging showed the ventrolateral medullar tegmentum containing the spinothalamic tract to be affected by lacunar infarction. The blink reflex R2 component was unimpaired in both patients.