“…[14][15][16] They do not always show high chemoselectivity. [18][19][20][21] Also they may employ potentially hazardous alkylating agents 14,18 or polluting solvents 15,17 and they may generate toxic by-products. 11,17 Moreover, the majority of the syntheses start from p-phenylenediamine, which is obtained from benzene in a multi-step process that has low atom economy.…”