Über den Kreislauf des Trainierten, über die Restblutmenge des Herzens und über die besondere Bedeutung röntgenologischer (kymographischer), hämodynamischer und elektrokardiographischer Beobachtungen in Ruhe und nach Belastung

Reindell, H

doi:10.1007/bf02120570

Cited by 12 publications

(2 citation statements)

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“…The extent to which Frank–Starling mechanisms or changes in myocardial contractility account for changes in the stroke volume and ejection fraction has been debated for decades. Despite early studies of heart function showing a fairly constant LVEDV at rest and during exercise but a smaller end‐systolic volume during exercise ( Reindell 1943, Kjellberg et al . 1949 ) many authors have favoured the idea that changes in SV are mainly because of changes in LVEDV according to the Frank–Starling mechanism of the heart.…”

Section: Discussionmentioning

confidence: 97%

“…Although Starling (1920) saw the limitations in this, the results from studies of lung–heart preparations, have been regarded applicable to the intact human heart, and considered as a central regulatory mechanism of the cardiac pump function. Early fluoroscopic in vivo studies of heart function by Reindell (1943) and Kjellberg et al . (1949 ) showed a fairly constant LVEDV at rest and during exercise but a smaller end‐systolic volume during exercise.…”

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confidence: 99%

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Left ventricular function in endurance runners during exercise

Jensen-Urstad

Bouvier

Nejat

et al. 1998

Acta Physiologica Scandinavica

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Left ventricular function in elite runners and controls was compared by means of nuclear angiocardiography. Fifteen middle- or long-distance runners and a control group of 10 sedentary to moderately physically active subjects were studied at rest and during semi-sitting incremental exercise. Ejection fraction was higher in the runners than the controls both at rest and during exercise. At the transition from rest to exercise left ventricular end-diastolic volume initially increased similarly in runners and controls by an average of 14 and 12%, respectively, with an increase in stroke volume by approximately 25 and 23%. The parallel increase in stroke volume and left ventricular end-diastolic volume could at least partly be because of the Frank-Starling mechanism. With increasing workloads, left ventricular end-diastolic volume and ejection fraction remained fairly constant, resulting in an unchanged stroke volume from the lowest to the highest exercise intensity. This was in the runners accomplished by a 41% increase in peak filling rate and a 38% increase in peak emptying rate with similar changes observed in the controls. This has to be due to increased myocardial contractility paralleling the systolic shortening with increasing heart rate. We conclude that endurance-trained athletes have a better systolic function expressed as higher ejection fraction both at rest and during exercise than untrained subjects reflecting an enhanced myocardial contractility contributing to the maintenance of a large stroke volume during exercise. The regulatory mechanisms however, appear to be similar for athletes and healthy controls.

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Section: Discussionmentioning

confidence: 97%

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confidence: 99%