-Observations dealing with the synthesis and properties of glycosides are reported. A description is given of the use of 1-Q-sulfonyl derivatives, prepared from aldoses with sulfonic anhydrides, as intermediates for the synthesis of glycosides and glycosyl halides; the synthesis of disaccharides containing ~mannopyranosyl residues receives particular attention. Glycosyl esters are formed by reactions of carboxylic acids with 1,2-alkyl orthoacetates. Measurements of 13c-1H coupling are discussed in relation to studies on the orientation of glycosidic bonds in di-and oligosaccharides, and to anomalaus spectral characteristics exhibited by glycosides of 5-thio-~-galactopyranose.