U<scp>ltrasound</scp> S<scp>timulation of</scp> M<scp>axillofacial</scp> B<scp>one</scp> H<scp>ealing</scp>

Schortinghuis, Jurjen; Stegenga, Boudewijn; Raghoebar, Gerry M.; Bont, Lambert G.M. de

doi:10.1177/154411130301400106

Cited by 45 publications

(48 citation statements)

References 67 publications

(107 reference statements)

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“…An investigation by Hollander (1972) using pulsed ultrasound of high frequency showed no adverse effects of any kind but Mannor et al (1972) using continuous ultrasound in the same frequency range observed increased rates of malformations, fetal resorption and low birth weight, thus, pointing to hyperthermia as the most probable teratogenic mechanism. Ultrasound is absorbed by tissues and converted into heat energy (Schortinghuis et al, 2003). Heating effects are the results of the absorption of ultrasound energy from an ultrasound beam (Gent, 1997).…”

Section: Discussionmentioning

confidence: 99%

Effect of multiple in-utero insonation on rabbit fetal thyroid hormonal level

Idris¹,

Audu²,

Fadason³

et al. 2017

Sokoto J. Vet. Sc.

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Due to the increased use of ultrasound in the diagnosis of cyesis, it is necessary to study the possible adverse effect of insonation on thyroid hormone in fetuses. Sixteen (16) adult rabbit does that had kindled at least once were used for the study and were scanned using a Medison S600V ® Ultrasound machine with a 6.5MHz transcutaneous curve-linear probe. All does were mated naturally by the introduction of a doe to a buck and then divided randomly into two groups. The does that were scanned (insonated)-, were properly restrained on dorsal recumbency, liberally shaved; aquasonic gel applied and scanned using a transcutaneous curve-linear probe for 5 minutes on the 5 th day post coitus and thereafter on days 7, 12, 15, 20, 25, 27 and 29. The restrain and scanning procedures were mimicked on the group of does that were not scanned (non-insonated). Upon parturition, blood was collected from kits and serum was extracted and used to assay for total thyroxine (tT4) and triiodothyronine (tT3). Fetal thyroid glands were also harvested for histologic study. Mean tT3 concentration was 1.60 ± 0.90 µg/dl and 1.58 ± 0.03 µg/dl while mean tT4 was 1.46 ± 0.10 µg/dl and 1.39 ± 0.07 µg/dl for the non-insonated and insonated groups, respectively. P values of 0.610 and 0.132 for tT3 and tT4 concentration respectively showed that there is no statistically significant difference in the values even though there was a numerical difference between the groups. No histopathologic change on fetal thyroid gland from both groups was observed. In conclusion, although the values were not significantly different, the numerical decrease of both tT3 and tT4 in the insonated rabbits suggest the possibility that insonation could alter their values in fetuses when the threshold of ultrasound waves are increased and insonation prolonged.

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Section: Discussionmentioning

confidence: 99%

Effect of multiple in-utero insonation on rabbit fetal thyroid hormonal level

Idris¹,

Audu²,

Fadason³

et al. 2017

Sokoto J. Vet. Sc.

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show abstract

“…It is difficult to explain this discrepancy because of the complicated interaction between the micromechanical forces of ultrasound and the bone healing process. In previous studies concerning mandibular bone defect healing in rats, no effect of daily 20 min ultrasound on bone defect healing could be observed [18][19][20]22 . Ultrasound may stimulate the endochondral ossification process in the extremities, but not the intramembranous ossification process present in the mand- ible.…”

Section: Discussionmentioning

confidence: 99%