U.S. state policies on opioid prescribing during the peak of the prescription opioid crisis: Associations with opioid overdose mortality

Buonora, Michele; Hanna, David B.; Zhang, Chenshu; Bachhuber, Marcus A.; Moir, Lorlette H.; Salvi, Pooja S.; Cunningham, Chinazo O.; Starrels, Joanna L.

doi:10.1016/j.drugpo.2022.103888

Cited by 7 publications

(4 citation statements)

References 30 publications

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“…Policy guidelines must be informed by research logistics, healthcare infrastructure, and reliable preclinical and clinical data, with the understanding that policies need to be constantly revisited, refined, and re-designed to accommodate the changing needs of the clinic and to correct the oversights of prior policy. Despite best intentions, U.S. state policies only modestly reduced opioid overdose mortality (Buonora et al, 2022) highlighting the complexity of the required framework that must go beyond the patient–clinician unit.…”

Section: Discussionmentioning

confidence: 99%

Pain Research and Treatment: Policy Implications

Tajerian,

Alvarado

2024

Policy Insights from the Behavioral and Brain Sciences

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Pain is a subjective experience for which we lack a thorough mechanistic understanding. While it has often been considered a secondary symptom of a disease, research has revealed that chronic pain can be recognized as a disease of its own. Preclinical studies often use animal models to understanding the pathology and test potential therapies with clinical trials of novel analgesics often showing underwhelming results. From a clinician's perspective, pain can be challenging to treat without incurring undesirable drug effects. Pain research, diagnosis, and treatment have changed dramatically over the last two decades. This has coincided with shifts in reliance on opioid-based approaches to managing pain. Here we present an overview of recent advances in preclinical research, novel approaches to diagnosis and treatment, along with considerations for animal care. Collectively, this report may provide a guide on which to base relevant policy changes that would meet the demands of societal need and satisfy the need for scientific evidence.

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Section: Discussionmentioning

confidence: 99%

Pain Research and Treatment: Policy Implications

Tajerian,

Alvarado

2024

Policy Insights from the Behavioral and Brain Sciences

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“…There are researches showing that the implementation of opioid-prescribing policies indeed decreases the amount of opioid prescriptions as well as overdoses resulting from them (Buonora et al, 2022;Beaudoin et al, 2016). However, other researchers have revealed that current state laws can unintentionally encourage people with opioid use disorders to seek the illicit market for drugs, thus increasing the overdose rate and suggesting that these types of legislation are not a strong deterrent (Lee et al, 2021;Bowen and Irish, 2019;Martins et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

The Impact of Opioid Prescribing Limits on Drug Usage in South Carolina: A Novel Geospatial and Time Series Data Analysis

Fakhrabad¹,

Sadeghi²,

Kemahlıoğlu‐Ziya³

et al. 2023

Preprint

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“…Studies on state-implemented policies to combat opioid misuse and overdose have produced inconsistent results [ 14 ]. While some studies suggest that policies such as dosage limits have reduced overdose deaths [ 15 ], others indicate that prescription drug monitoring programs have only had a small effect on opioid shipments [ 16 ] and that these laws are not very effective [ 17 ]. Research on the effectiveness of opioid limit laws enacted mostly after 2017 is also limited, and analysis of their impact on the entire opioid supply chain, including prescribers and dispensers, is lacking in the literature [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Opioid Prescribing Limits on Drug Usage in South Carolina: A Novel Geospatial and Time Series Data Analysis

et al. 2023

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The opioid crisis in the United States has had devastating effects on communities across the country, leading many states to pass legislation that limits the prescription of opioid medications in an effort to reduce the number of overdose deaths. This study investigates the impact of South Carolina’s prescription limit law (S.C. Code Ann. 44-53-360), which aims to reduce opioid overdose deaths, on opioid prescription rates. The study utilizes South Carolina Reporting and Identification Prescription Tracking System (SCRIPTS) data and proposes a distance classification system to group records based on proximity and evaluates prescription volumes in each distance class. Prescription volumes were found to be highest in classes with pharmacies located further away from the patient. An Interrupted Time Series (ITS) model is utilized to assess the policy impact, with benzodiazepine prescriptions as a control group. The ITS models indicate an overall decrease in prescription volume, but with varying impacts across the different distance classes. While the policy effectively reduced opioid prescription volumes overall, an unintended consequence was observed as prescription volume increased in areas where prescribers were located at far distances from patients, highlighting the limitations of state-level policies on doctors. These findings contribute to the understanding of the effects of prescription limit laws on opioid prescription rates and the importance of considering location and distance in policy design and implementation.

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U.S. state policies on opioid prescribing during the peak of the prescription opioid crisis: Associations with opioid overdose mortality

Cited by 7 publications

References 30 publications

Pain Research and Treatment: Policy Implications

Pain Research and Treatment: Policy Implications

The Impact of Opioid Prescribing Limits on Drug Usage in South Carolina: A Novel Geospatial and Time Series Data Analysis

The Impact of Opioid Prescribing Limits on Drug Usage in South Carolina: A Novel Geospatial and Time Series Data Analysis

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