Typing of Neisseria meningitidis by restriction analysis of the amplified porA gene

Long-Term Persistence of a Discotheque-Associated Invasive Neisseria meningitidis Group C Strain as Proven by Pulsed-Field Gel Electrophoresis and porA Gene Sequencing

“…Isolates may change their phenotype by, for example, capsular switching, justifying approaches other than serogroup typing when disease-causing strains are traced (19). In addition to the standard pulsed-field gel electrophoresis (PFGE) (15,19), multilocus enzyme electrophoresis (13), ribosomal DNA restriction profiles (21), and PCR analysis followed by restriction fragment length polymorphism analysis of the porA gene have, among other methods, been used for characterization of N. meningitidis serogroup C (5,14).…”