Typing and nosocomial candidiasis

Maffei, C.; Manso, Esther; Biavasco, Francesca; Varaldo, Pietro E.; Moro, Maria Luisa

doi:10.1128/jcm.28.5.1086-1087.1990

J Clin Microbiol

1990

DOI: 10.1128/jcm.28.5.1086-1087.1990

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Typing and nosocomial candidiasis

C. Maffei¹,

Esther Manso²,

Francesca Biavasco³

et al.

Abstract: hominis infection presenting as recurrent diarrhea. Ann. Intern. Med. 102:495-496.

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Cited by 3 publications

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“…Maffei et al (6) suggested that DNA typing of the C. tropicalis isolates reported by Isenberg et al (5) would have definitively implicated the scrub nurse as the source of the outbreak. However, few data are available regarding the molecular typing of C. tropicalis.…”

mentioning

confidence: 99%

Restriction fragment analysis of a Candida tropicalis outbreak of sternal wound infections

et al. 1991

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An apparent single-source outbreak of Candida tropicalis sternal wound infections in eight patients was investigated by utilizing DNA restriction fragment analysis (RFA) with Hindlll and BstNI. All eight outbreak isolates appeared to be identical and were easily differentiated from control isolates by DNA RFA. Compared with an arbitrarily selected reference outbreak isolate,-95% of the bands in the restriction digests identified by a computerized image analysis system from each of the outbreak isolates were identical versus 13 to 53% of the bands in any of the nine control isolates. Outbreak strains were significantly more likely to match the reference outbreak isolate than were controls (P < 0.0001). The RFA was greatly facilitated by the use of computerized image analysis and confirmed the epidemiologic link between a scrub nurse and the infected patients.

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mentioning

confidence: 99%

Restriction fragment analysis of a Candida tropicalis outbreak of sternal wound infections

et al. 1991

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New laboratory techniques for hospital infection control

McGowan

1991

The American Journal of Medicine

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Multilocus enzyme electrophoresis analysis of Candida albicans isolates from three intensive care units. An epidemiological study

Arnavielhe¹,

Blancard²,

Mallié³

et al. 1997

Mycoses

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To evaluate the mechanism and risk factor associated with the nosocomial acquisition of Candida albicans, a 3-month prospective study was conducted on non-neutropenic patients in three distinct intensive care units in distinct hospitals. A total of 43 samples from 19 patients has been typed by multilocus enzyme electrophoresis (MEE). Samples (24) from the deep pharynx of hospital staff members were also cultured and typed. Thirteen of the 19 enzyme loci studied were polymorphic. The 52 electrophoretic types were assigned to 67 isolates, each type was represented by one to five isolates; this proved the great diversity of the isolates. It appeared that most patients were colonized or infected with different C. albicans strains. This study pointed out a possible cross-infection between patients and hospital staff and between healthy members of the hospital staff, and also showed the successive stages of infection by different electrophoretic types. Intubation and respiratory equipment as surgery intervention were possible sources of observed infections.

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Typing and nosocomial candidiasis

Abstract: hominis infection presenting as recurrent diarrhea. Ann. Intern. Med. 102:495-496.

Cited by 3 publications

References 25 publications

Restriction fragment analysis of a Candida tropicalis outbreak of sternal wound infections

Restriction fragment analysis of a Candida tropicalis outbreak of sternal wound infections

New laboratory techniques for hospital infection control

Multilocus enzyme electrophoresis analysis of Candida albicans isolates from three intensive care units. An epidemiological study

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