Typical Radiological Features of a Rare Lateral Ventricular Liponeurocytoma

Shen, Sisi; Tang, Yu; Yang, Ruiyi; Zhou, Dong

doi:10.1002/ana.26207

Cited by 1 publication

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of those, 18 cases demonstrate recurrence following resection of the primary tumor. [ 1 , 2 , 6 - 8 , 10 , 11 , 14 - 17 , 19 , 21 , 22 , 24 , 25 ] Only seven cases thus far have reported a second tumor recurrence. [ 1 , 2 , 11 , 14 , 21 , 22 ]…”

Section: Introductionmentioning

confidence: 99%

“…Of those, 18 cases demonstrate recurrence following resection of the primary tumor. [1,2,[6][7][8]10,11,[14][15][16][17]19,21,22,24,25] Only seven cases thus far have reported a second tumor recurrence. [1,2,11,14,21,22] Here, we report a case of liponeurocytoma which recurred following two gross total resections (GTRs), along with a review of the 18 previously reported cases of recurrent liponeurocytoma with the hope of improving understanding of histopathological changes that occur with recurrence as well as guiding treatment and surgical decision-making in the treatment of this rare but intransigent entity.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Recurrent liponeurocytoma: A case report and systematic review of the literature

Shah

Sharma

Patel

et al. 2022

Surgical Neurology International

View full text Add to dashboard Cite

Background: Liponeurocytomas are rare neurocytic neoplasms that most often arise in the posterior fossa and affect individuals in the third and fifth decades of life. Most reported cases of this unique tumor in the literature have described a favorable clinical prognosis without recurrence. However, increasing reports of recurrent cases prompted the World Health Organization, in 2016, to recategorize the tumor from Grade I to the less favorable Grade II classification. We conducted a systematic review to identify recurrent cases of this unique tumor and to summarize differences between the primary and recurrent cases of liponeurocytoma. Methods: A systematic review exploring recurrent liponeurocytoma cases was conducted by searching the PubMed, Google Scholar, and Scopus databases for articles in English. Abstracts from articles were read and selected for full-text review according to a priori criteria. Relevant full-text articles were analyzed for symptoms, imaging, location, histological, pathological, treatment, and recurrence-free time between the primary and recurrent cases. Results: Of 4392 articles, 15 articles accounting for 18 patients were included (level of evidence: IV) in the study. Recurrence-free time decreased from an average of 82 months between the primary tumor resection to first recurrence to 31.3 months between the first and second recurrence. Recurrent tumors demonstrated increased pleomorphic neural cells, necrosis, vascular proliferation, and MIB-1 index when compared to the primary tumor. Several cases also demonstrated decreased lipidizing components when compared to the primary tumor, further indicating increased dedifferentiation. The primary treatment for this tumor was surgical resection with occasional adjunctive radiotherapy. Conclusion: Recurrent cases of liponeurocytoma have features of increased malignant proliferation compared to the primary cases. The standard treatment for these primary and recurrent tumors is gross total resection. The role of adjunctive radiotherapy remains a matter of debate.

show abstract