Typhoid glomerulonephritis and intestinal perforation in a Nigerian child

Abstract

The number of children with renal complications following salmonella infection cannot be precisely defined in the sub-Saharan Africa due to scarcity of reliable data. We report a 3-year-old boy with glomerulonephritis secondary to typhoid infection and later intestinal perforation. He presented with fever, generalized body swelling, oliguria, coke- colored urine and hypertension and had been managed 3 weeks earlier for typhoid fever in a private hospital. Laboratory investigations showed proteinuria, hematuria with red cell casturia and azotemia. Abdominal X-ray done was suggestive of typhoid intestinal perforation that was confirmed at exploratory laparotomy. He was managed aggressively with antibiotics and was discharged on the 25 th day of admission. To the best of our knowledge, this is the first documented case report of acute glomerulonephritis and intestinal perforation as co-complications of salmonella infection in Nigeria.

Rhabdomyolysis and acute kidney injury in Salmonella gastroenteritis: A case report

“…The occurrence of acute kidney injury in many patients is believed due to dehydration from gastroenteritis, tissue hypoxia from sepsis, rhabdomyolysis, nephrotoxicity of myoglobin [14]. Other rare causes of acute kidney injury in Salmonella infection include glomerulonephritis, acute tubular necrosis (ATN) and interstitial nephritis [4,18].…”

Impact of Stress on Academic Staff: Implication for Higher Education Management and Leadership

“…Furthermore, stress has manifested in the way lecturers respond to forces in the academic environment. Some of them are expected to meet some unrealistic targets without facilities being provided (Odetunde, 2004). Facilities provided in Nigerian universities are insufficient for student and teacher needs (Adeyemi & Igbineweka, 2000;Babatope, 2010).…”