Typhoid encephalopathy in children

Pohowalla, J. N.; Op, Ghai

doi:10.1007/bf02823153

Cited by 12 publications

(6 citation statements)

References 3 publications

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“…Psychiatric manifestations include temporary amnesia, schizophrenia and rarely hypomania. Basal ganglia disorders are well described—a transient Parkinson’s syndrome is seen in about 2% of cases6 while choreiform movements are well described in children with typhoid 7 8…”

Section: Discussionmentioning

confidence: 99%

Catatonia and parkinsonism as a sequelae of typhoid fever: a rare experience

Talukdar

Dutta

Rana³

et al. 2013

BMJ Case Reports

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Although neurological manifestations of typhoid fever was thought to be obsolete from modern world, emergence of multidrug resistant typhoid bacilli and reporting of outbreak of typhoid fever with a range of early neuropsychiatric manifestations from various parts of world has led clinicians and investigators to re-evaluate the clinical spectrum of this endemic sinister disease. An 18-year-old male student was admitted in psychiatry ward with mutism, staring look, posturing and rigidity. There was history of typhoid fever 1 week before for which he was prescribed cefuroxime. Although investigations fail to provide any clue, his catatonic symptoms disappeared 2 weeks later giving way to resting tremor, bradykinesia, cog-wheel rigidity but without gait abnormality. He was successfully treated with lorazepam, amantidine, olanzapine and pramiprexole. The patient was asymptomatic within a month. He had no recurrence of symptoms till last follow-up, 6 months from the illness.

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Section: Discussionmentioning

confidence: 99%

Catatonia and parkinsonism as a sequelae of typhoid fever: a rare experience

Talukdar

Dutta

Rana³

et al. 2013

BMJ Case Reports

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“…This child remained mute for 8 weeks but made a complete recovery. Examples of aphasia unassociated with hemiplegia in the course of typhoid fever in children have been reported by Olser (1895a), Smith (1911), Pohowalla and Ghai (1957), and Pohowalla (1965). The nature of the lesion responsible for the aphasia is not known but it has been postulated that it is an encephalitis.…”

Section: Neurological Complicationsmentioning

confidence: 94%

“…In our group of infants under 2 years of age the duration of symptoms was not significantly shorter than in the older child. Sood and Taneja (1961a) believed that there was no typical clinical picture of typhpid fever in children, and Pohowalla (1965) stated that as a rule the classical features of this disease described in textbooks were absent in children. Nevertheless, in this series the correct diagnosis of typhoid fever was made by the admitting officer in 66% of cases, though a family history did aid in the diagnosis in a few instances.…”

Section: Duration Of Historymentioning

confidence: 99%

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Typhoid fever in African and Indian children in Durban.

Scragg¹,

Rubidge²,

Wallace³

1969

Archives of Disease in Childhood

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“…We are currently undertaking studies with the electron microscope in an attempt to substantiate this hypothesis. Medical3Journal, 1975, 1, 494-495 Encephalopathy with focal neurological signs and altered consciousness is a rare complication of typhoid fever and carries a high mortality (Roger and Gastaut, 1945;Pohowalla and Ghai, 1957;Zellweger and Idriss, 1960;Aita, 1972). The pathological changes in the brains of such patients, however, are poorly documented in the literature.…”

mentioning

confidence: 99%