Typhlitis

Dworkin, B.; Winawer, Sidney J.; Lightdale, Charles J.

doi:10.1007/bf01314769

Cited by 34 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Neutropenic enterocolitis (NE) affects the terminal ileum and/or colon (cecum) and is almost exclusively found in neutropenic patients [4]. Enterocolitis is the most common abdominal disease in patients with febrile neutropenia and affects up to 50% of patients after chemotherapy [5].…”

Section: Introductionmentioning

confidence: 99%

A Novel Severity Score Index for Febrile Neutropenic Patients with Colorectal Diseases

Perazzoli

Parra

Feitosa

et al. 2019

Gastroenterology Research and Practice

View full text Add to dashboard Cite

Introduction. Abdominal and anorectal disorders may be the cause of clinical decompensation in neutropenic febrile patients, particularly those with hematologic diseases. Infection is a cause for concern for the colorectal surgeon. Some conditions have few manifestations and can lead to death within a short period of time. This study presents the novel colorectal disorder severity score for febrile neutropenic patients. Materials and Methods. This was a case series study analyzing the medical records of 897 patients admitted to the Hematology and Hematopoietic Stem Cell Transplant Unit in a university hospital between the years 2008 and 2013. Seventy-four episodes of febrile neutropenia in 69 patients diagnosed with an abdominal or anorectal infection site were eligible for the study. The new scoring system proposed here is based on the author’s clinical experience and an extensive literature review. In addition to the extensive literature review, effect measures were calculated, and a statistical analysis was performed. Based on an evaluation of common biological plausibility criteria, five factors were selected as the main predictors of hospital mortality in febrile neutropenic patients with colorectal disease. Results. The proposed score demonstrated increased mortality as the condition worsened as reflected by an increasing score (Fisher’s exact test: 0.001). When considering the logistic model for the probability of death by score level, the AUC value was 0.82 (0.72-0.925), and the Hosmer-Lemeshow statistic value was 2.3, p=0.806. Conclusion. The proposed scoring system allows prediction of the likelihood of death during hospitalization for febrile neutropenic patients with an abdominal and anorectal focus. New studies on the subject are required, and the proposed scoring scale must be validated on a larger and different sample of patients.

show abstract

Section: Introductionmentioning

confidence: 99%

A Novel Severity Score Index for Febrile Neutropenic Patients with Colorectal Diseases

Perazzoli

Parra

Feitosa

et al. 2019

Gastroenterology Research and Practice

View full text Add to dashboard Cite

show abstract

Neutropenic Enterocolitis in Adults With Acute Leukemia

Mower¹

1986

Arch Surg

View full text Add to dashboard Cite

Acute lymphoblastic leukemia presenting with typhlitis

Kaste

Flynn

Furman

1997

Med. Pediatr. Oncol.

View full text Add to dashboard Cite

We report an unusual case of acute lymphoblastic leukemia (ALL) that presented as right lower quadrant pain in a 17‐year‐old boy. Ultrasonographic findings were consistent with typhlitis. The clinical and imaging symptoms resolved upon treatment with antibiotics and conservative care, only to recur after initiation of chemotherapy. Familiarity with the clinical presentation and imaging findings of typhlitis is important for its correct diagnosis and management. Med. Pediatr. Oncol. 28:209–212 © 1997 Wiley‐Liss, Inc.

show abstract

Typhlitis

Cited by 34 publications

References 30 publications

A Novel Severity Score Index for Febrile Neutropenic Patients with Colorectal Diseases

A Novel Severity Score Index for Febrile Neutropenic Patients with Colorectal Diseases

Neutropenic Enterocolitis in Adults With Acute Leukemia

Acute lymphoblastic leukemia presenting with typhlitis

Contact Info

Product

Resources

About