Types of Imaging, Part 3: Atomic Force Microscopy

Jensen, Ellen C.

doi:10.1002/ar.22605

Cited by 1 publication

(1 citation statement)

References 43 publications

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“…AFM is a high-resolution, scanning probe microscopic technique which can provide information about surface topology of the nanomaterial/nanocomposite and local properties like surface thickness, height, friction, or magnetism based on the interaction between the sharp tip of cantilever probe and the material surface. , In addition, it enables determination of the properties of adsorbed protein (elasticity, Young’s modulus, etc. ), and the effects of interaction between protein and nanosheet (protein folding and unfolding, agglomeration, etc.).…”

Section: Analytical Methods For Evaluation Of 2d Nanomaterial–protein...mentioning

confidence: 99%

Nanobio Interface Between Proteins and 2D Nanomaterials

Roy

Aastha

Deo

et al. 2023

ACS Appl. Mater. Interfaces

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nanomaterials have significantly contributed to recent advances in material sciences and nanotechnology, owing to their layered structure. Despite their potential as multifunctional theranostic agents, the biomedical translation of these materials is limited due to a lack of knowledge and control over their interaction with complex biological systems. In a biological microenvironment, the high surface energy of nanomaterials leads to diverse interactions with biological moieties such as proteins, which play a crucial role in unique physiological processes. These interactions can alter the size, surface charge, shape, and interfacial composition of the nanomaterial, ultimately affecting its biological activity and identity. This review critically discusses the possible interactions between proteins and 2D nanomaterials, along with a wide spectrum of analytical techniques that can be used to study and characterize such interplay. A better understanding of these interactions would help circumvent potential risks and provide guidance toward the safer design of 2D nanomaterials as a platform technology for various biomedical applications.

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Section: Analytical Methods For Evaluation Of 2d Nanomaterial–protein...mentioning

confidence: 99%