“…Interestingly, in the Asian variant of IVLBCL, there is an associated hemophagocytic component which includes hepatosplenic involvement and cytopenia. Hemophagocytic lymphohistiocytosis (HLH) secondary to IVLBCL can present with a wide variety of symptoms and lab abnormalities, but is most commonly seen with fever, bicytopenia, splenomegaly, and ferritin greater than 500 mcg/L, and can be confirmed at times with biopsy showing hemophagocytosis in the setting of the IVLBCL diagnosis [ 4 , 5 ].…”