Type A competitiveness traits correlate with downregulation of c-Fos expression in patients with type 1 diabetes

Chauvet-Gélinier, Jean-Christophe; Mosca-Boidron, Anne-Laure; Lemogne, Cédric; Ragot, Sylviane; Forestier, Nicole; Callegarin, D.; Allard, Catherine; Rebai, Ahmed; Bouillet, Benjamin; Ponavoy, Eddy; Simoneau, Isabelle; Petit, Jean‐Michel; Bondolfi, Guido; Callier, Patrick; Trojak, Benoît; Bonin, Bernard; Vergès, Bruno

doi:10.1016/j.diabet.2018.11.005

Diabetes & Metabolism

2019

DOI: 10.1016/j.diabet.2018.11.005

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Type A competitiveness traits correlate with downregulation of c-Fos expression in patients with type 1 diabetes

Jean-Christophe Chauvet-Gélinier

Anne-Laure Mosca-Boidron

Cédric Lemogne

et al.

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Cited by 4 publications

(1 citation statement)

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“…Certain aspects of this personality type -not expressing negative feelings, especially suppressing hostility -have been recognized as being a significant cause of ischemic heart disease. It was recognized that they may be more unfavorable to health than other components and may increase the risk of various other diseases, not only ischemic heart disease as previously thought [17,18]. Various researchers tend to believe that personality type A may also contribute to the development of other somatic diseases such as gastric and duodenal ulcers, digestive system diseases, and rheumatic disease [15,19].…”

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Personality traits favourable for non-adherence to treatment in patients with chronic myeloid leukaemia: role of type A and D personality

Rychter

Miniszewska

Góra‐Tybor

2023

BioPsychoSocial Med

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Background The introduction of BCR-ABL tyrosine kinase inhibitors (TKIs) to chronic myeloid leukemia (CML) therapy has revolutionized the treatment of this disease. Although regular TKI intake is a prerequisite for successful therapy, it has been shown that a significant proportion of patients are non-compliant. Recently there is growing evidence that personality traits may influenced the tendency for non-adherence to treatment in patients with chronic diseases. As far as we know, such a relationship in patients with CML has not been examined, yet. The aim of our study was to determine if personality traits favor non-adherence to treatment recommendations. We investigated the relationship between five-factor model personality factors (conscientiousness, neuroticism, agreeableness, extraversion, and openness) and medication non-adherence. We also checked if the patients with type A and type D personality, were at higher risk of poor medication adherence. Methods The following tools were used: self-constructed survey, the NEO-Five Factor Inventory, the Framingham Type A Scale, the D-Scale 14. The study included 140 CML patients treated with imatinib, dasatinib, or nilotinib. Results 39% of patients reported skipping at least one dose of medication in the month prior to follow-up visit. 51% admitted to skipping such doses from the start of their treatment to the time at which our assessment was performed. We did not find any relationship between the mean values of the analyzed factors of the Big Five (neuroticism, extraversion, openness, agreeableness, conscientiousness) and adherence. However, our analysis revealed that CML patients who admitted to missing doses of drugs during the entire course of treatment demonstrated greater intensity of type A personality traits (p = 0.020). Regarding both factors of type D personality, it was revealed that higher level of negative affectivity significantly decreased the adherence (p = 0.020). Conclusion The results of our study indicate that screening for type D and A personalities may help to identify patients who are at higher risk of poor medication adherence.

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Personality traits favourable for non-adherence to treatment in patients with chronic myeloid leukaemia: role of type A and D personality

Rychter

Miniszewska

Góra‐Tybor

2023

BioPsychoSocial Med

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Fewer Type A personality traits in type 2 diabetes patients with diabetic foot ulcer

Vergès

Brands

Fourmont

et al. 2021

Diabetes & Metabolism

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Profils de personnalité et diabète : des associations troublantes

Vergès,

Rouland

2024

Médecine des Maladies Métaboliques

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Type A competitiveness traits correlate with downregulation of c-Fos expression in patients with type 1 diabetes

Cited by 4 publications

References 26 publications

Personality traits favourable for non-adherence to treatment in patients with chronic myeloid leukaemia: role of type A and D personality

Personality traits favourable for non-adherence to treatment in patients with chronic myeloid leukaemia: role of type A and D personality

Fewer Type A personality traits in type 2 diabetes patients with diabetic foot ulcer

Profils de personnalité et diabète : des associations troublantes

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