Type 2 Diabetes Mellitus in Ambulatory Adult Nigerians: Prevalence and Associated Family Biosocial Factors in a Primary Care Clinic in Eastern Nigeria: A Cross-sectional Study

Iloh, Gabriel Uche Pascal; Amadi, AN; Ebirim, Chikere Ifeanyi Casmir

doi:10.9734/bjmmr/2015/18783

Cited by 9 publications

(2 citation statements)

References 41 publications

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“…Both Tsai et al and Bagchi et al's studies were done 10 years earlier, while Raji et al's study was done 6 years earlier than this study 24,26,27 . The prevalence of DM in this study was also higher than 4.7% reported by Iloh et al among adults in South-east Nigeria, although, their study was done 6 years earlier 59 . Familial clustering may also explain the higher prevalence of DM obtained in this study.…”

Section: Risk Factors For Ckd In Fdrs Of Ckd Patientscontrasting

confidence: 66%

Risk factors for Undiagnosed Kidney Disease among Stable First-Degree Relatives of Chronic Kidney Disease Patients at Nnamdi Azikiwe University Teaching Hospital, Nnewi, South Eastern Nigeria

Ozuemba,

Ezeude,

Odenigbo

et al. 2024

J. Drug Delivery Ther.

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Background: Chronic kidney disease (CKD) is a global public health problem and has a major impact on health and cost of health care. In Nigeria, renal replacement therapy (RRT) is funded out of pockets by patients and their relatives unlike in most developed countries. There is a high clustering of the risk factors for CKD in FDRs of CKD patients, making then an ideal population for the screening for and the reversal of the modifiable risk factors that predispose to CKD. Objective: This study determined the risk factors for CKD in the FDRs of patients Methodology: This study involving 300 subjects: 150 FDRs of CKD patients and 150 control subjects without personal or family history of CKD. The study and control subjects were screened for CKD using urine albumin creatinine ratio (uACR) and estimated glomerular filtration rate (eGFR). Prevalence rate of the risk factors for CKD such as hypertension, diabetes mellitus, obesity, dyslipidaemia, hyperuricaemia and life style practices like significant smoking and heavy alcohol consumption were determined for both the FDRs and the control subjects. Data was analyzed with SPSS version 21.0. Mann-Whitney U test was used for comparing the variables between the two study groups for continuous variables that were not normally distributed and Chi square tests for categorical variables. Results: The prevalence rate of dyslipidaemia and hyperuricaemia was significantly higher among the FDRs of CKD patients compared with the control subjects (26% versus 12%; P = 0.003) and (20.7% versus 7.3%; P = 0.001) respectively. The other risk factors for CKD that included hypertension, diabetes mellitus, obesity, significant cigarette smoking, heavy alcohol consumption and herbal medication use were equally more among the FDRs of CKD patients compared with the controls, although not statistically significant. Conclusion: The risk factors for CKD were common among FDRs of CKD patients. Screening for these risk factors at the earliest possible contact with the FDRs of CKD patients and taking appropriate actions to tackle the modifiable ones will prevent the development of CKD and retard the progression of the already existing disease, reduce the alarming global burden of CKD.

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Section: Risk Factors For Ckd In Fdrs Of Ckd Patientscontrasting

confidence: 66%

Risk factors for Undiagnosed Kidney Disease among Stable First-Degree Relatives of Chronic Kidney Disease Patients at Nnamdi Azikiwe University Teaching Hospital, Nnewi, South Eastern Nigeria

Ozuemba,

Ezeude,

Odenigbo

et al. 2024

J. Drug Delivery Ther.

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“…In Oke -Ogun, South West, Nigeria, Rasaki et al 2 found that T2DM is more common among females below 61 years due to abject poverty. The Iloh et al's study 38 found that T2DM was more prevalent in middle-aged adults than in younger adults in Nigeria. The increased T2DM is associated with the rapid urbanization in Nigeria and the lack of knowledge of most people not eating their local healthy foods and instead eating processed foods 39 .…”

Section: Discussionmentioning

confidence: 95%

Prevalence of prediabetes in an urban Nigerian population using the Finnish Diabetes Risk Score

Sowunmi

Bhakta

2022

Nor. Afr. J. Food Nutr. Res.

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Background: Type 2 Diabetes Mellitus (T2DM) is a global problem in emerging economy Nigeria. Early detection can help delay or prevent the disease. Aims: This study aims to characterize the prevalence of prediabetes in the study population using the validated Finnish Diabetes Risk Score (FINDRISC) in the adult population in an urban Sagamu Ogun State South-Western Nigeria. Patients and Methods: Healthy participants (n=581) aged 18-65yrs with no known history of T2DM or pregnancy were recruited from local urban churches in Sagamu. The FINDRISC questionnaire was then administered, which included questions on age, BMI, waist circumference, vegetable consumption, physical activity, history of high blood pressure, family history of T2DM and history of high blood sugar. Results: Overall, 51.8% of the participants were assigned a risk of developing T2DM in the next 10 years, with a range of categories from slightly elevated to very high risk; 34.4% of the participants had a risk score of 7-11, indicating a slightly elevated risk; 11.2% of the participants had a risk score of 12-14, indicating a moderately elevated risk, while 5.3% of the participants had a risk score of 15-20, indicating a high risk and 0.9% of the participants had a risk score higher than 20 indicating very high elevated risk. The gender distribution of the risk scores showed that 1.7% of the males and 9.5% of the females had a moderate to high risk (score ≥ 12) of developing T2DM in the next 10 years. The FINDRISC score was positively and significantly correlated with body weight (r=0.49; p<0.001), BMI (r=0.55; p<0.001) and age (r=0.27; p<0.001). This prevalence of prediabetes is similar to that found in other studies in Nigeria. Conclusion: This study confirms the use of this simple and non-invasive screening tool for T2DM among adults in Nigeria. It is also a useful tool to increase awareness of this condition in the population.

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Prevalence and Risk Factors for Diabetes Mellitus in Nigeria: A Systematic Review and Meta-Analysis

et al. 2018

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IntroductionThere has been no nationwide health (diabetes) survey in Nigeria since 1992, when a diabetes mellitus (DM) prevalence of 2.2% was reported. We aimed to determine the prevalence of and risk factors for DM in Nigeria by performing a systematic review and meta-analysis.MethodsWe searched Medline, EMBASE, PubMed, PapersFirst, the Cochrane Library, Scopus, Bioline, African Journals Online, Institute of Scientific Information, and Google Scholar from the year 1990 to 2017. Using MeSH headings, the terms “diabetes mellitus,” “risk factors,” “prevalence,” and “Nigeria” as well as variations thereof were searched for. The last search was performed on 26 November 2017. We only included studies that utilized the random plasma glucose test, the fasting plasma glucose test, the oral glucose tolerance test (OGTT), or HbA1c to diagnose DM. A total of 23 studies (n = 14,650 persons) were evaluated. A random effects model was used to estimate the pooled prevalence of DM. We estimated the overall pooled prevalence of DM and subgroup-specific DM prevalences while accounting for inter-study and intra-study variability/heterogeneity.ResultsThe overall pooled prevalence of DM was 5.77% (95% CI 4.3–7.1). The pooled prevalences of DM in the six geopolitical zones of Nigeria were 3.0% (95% CI 1.7–4.3) in the north-west, 5.9% (95% CI 2.4–9.4) in the north-east, 3.8% (95% CI 2.9–4.7) in the north-central zone, 5.5% (95% CI 4.0–7.1) in the south-west, 4.6% (95% CI 3.4–5.9) in the south-east, and 9.8% (95% CI 7.2–12.4) in the south-south zone. Risk factors for the pooled prevalence of DM were a family history of DM (4.6%; 95% CI 3.5–5.6); urban dwelling (6.0%; 95% CI 4.3–7.8); unhealthy dietary habits (8.0%; 95% CI 5.4–10.5); cigarette smoking (4.4%; 95% CI 1.3–10.2); older age (6.6%; 95% CI 4.5–8.7); physical inactivity (4.8%; 95% CI 3.2–6.4); and obesity (5.3%; 95% CI 3.8–6.9).ConclusionThere has been an increase in the prevalence of DM in Nigeria. All regions of the country have been affected, with the highest prevalence seen in the south-south geopolitical zone. Urban dwelling, physical inactivity, advanced age, and unhealthy diet are important risk factors for DM among Nigerians. A national diabetes care and prevention policy is highly recommended.

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Type 2 Diabetes Mellitus in Ambulatory Adult Nigerians: Prevalence and Associated Family Biosocial Factors in a Primary Care Clinic in Eastern Nigeria: A Cross-sectional Study

Cited by 9 publications

References 41 publications

Risk factors for Undiagnosed Kidney Disease among Stable First-Degree Relatives of Chronic Kidney Disease Patients at Nnamdi Azikiwe University Teaching Hospital, Nnewi, South Eastern Nigeria

Risk factors for Undiagnosed Kidney Disease among Stable First-Degree Relatives of Chronic Kidney Disease Patients at Nnamdi Azikiwe University Teaching Hospital, Nnewi, South Eastern Nigeria

Prevalence of prediabetes in an urban Nigerian population using the Finnish Diabetes Risk Score

Prevalence and Risk Factors for Diabetes Mellitus in Nigeria: A Systematic Review and Meta-Analysis

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