Type 2 diabetes mellitus in a cohort of Finnish patients with hidradenitis suppurativa

Kluger, Nicolas; Nuutinen, Pauliina; Lybeck, Emilia; Ruohoalho, Timo; Salava, Alexander

doi:10.1111/jdv.16010

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…The association of TD and higher BMI may be due to the majority of hypothyroidism among TD patients. We previously showed that Finnish patients with T2DM had a more severe disease according to Hurley staging [8]. TD has also been associated with an increased severity of HS [5].…”

Section: Discussionmentioning

confidence: 99%

Thyroid Diseases in a Cohort of Finnish Patients with Hidradenitis Suppurativa

Kluger¹

2023

Skin Appendage Disord

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Introduction: The association between thyroid disorders (hyperthyroidism or hypothyroidism) and hidradenitis suppurativa is controversial. Our study aimed to determine the phenotype and comorbidities of HS patients with thyroid disorders. Methods: A retrospective study was conducted in the department of dermatology, Helsinki University Hospital, Finland, and included all the attending patients with HS diagnosis in 2018. Results: A total of 167 patients were included (97 women). The prevalence of thyroid disorders was 12% and of hypothyroidism 10.7%. Patients with thyroid disorders were more likely to have a BMI ≥25 (p = 0.016), asthma (p = 0.034) and to be nonsmoker (p = 0.018) or ex-smoker (p = 0.017). Binary logistic regression showed that only asthma and nonsmoking were associated with thyroid disorders or hypothyroidism among patients with HS. Conclusion: Our study is in line with previous ones that showed the association of HS and thyroid disorders in nonsmokers. Asthma may be simply an association with thyroid disorders and unrelated to HS as such.

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Section: Discussionmentioning

confidence: 99%

Thyroid Diseases in a Cohort of Finnish Patients with Hidradenitis Suppurativa

Kluger¹

2023

Skin Appendage Disord

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“…Some authors stated that several dermatoses like hidradenitis suppurativa (38), glucagonoma (39), eruptive xanthoma (40), lipoid proteinosis (41), Kyrle disease (42), carotenoderma, and psoriasis vulgaris are more common in diabetes. The latter remains a controversy but these diseases represent metabolic disturbances.…”

Section: Vitiligomentioning

confidence: 99%

Dermatoses Associated with Diabetes Mellitus

Dourmishev

Pozharashka

2020

J Skin Stem Cell

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Context: Diabetes is considered a major health problem, mainly due to its various debilitating complications, including blindness, renal failure, heart attack, stroke, limb amputation, and even death in millions of patients per year. Skin manifestations of diabetes are common in everyday clinical practice but often remain neglected. This review aims to highlight the pathogenetic mechanisms and clinical picture of skin conditions, associated with diabetes mellitus. Evidence Acquisition: The skin manifestations of diabetes mellitus are related to blood glucose levels. Initially, glycemia affects skin homeostasis by inhibiting keratinocyte proliferation and phagocytosis and inducing endothelial cell apoptosis, while in later stages, the involvement of the peripheral nervous system and vascular changes (micro and macroangiopathy) become the leading pathogenetic factors. Results: There are different classifications of skin changes in diabetes, depending on the frequency, the onset, or the type of diabetes. The most convenient classification from the practical point of view subdivides cutaneous manifestations into four categories: (A) cutaneous manifestation specific to diabetes; (B) compatible dermatosis not specific to diabetes; (C) skin infection associated with diabetes; and (D) skin manifestation due to antidiabetic therapy. Conclusions: Diabetes mellitus is associated with a wide range of dermatological disorders. Their recognition is important for the early diagnosis of diabetes and therefore might be helpful to reduce the complication rates.

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Type 2 diabetes mellitus in a cohort of Finnish patients with hidradenitis suppurativa

Cited by 2 publications

References 8 publications

Thyroid Diseases in a Cohort of Finnish Patients with Hidradenitis Suppurativa

Thyroid Diseases in a Cohort of Finnish Patients with Hidradenitis Suppurativa

Dermatoses Associated with Diabetes Mellitus

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