Type 2 diabetes in children and adolescents: Exploring the disease heterogeneity and research gaps to optimum management
Subhodip Pramanik,
Sunetra Mondal,
Rajan Palui
et al.
Abstract:Over the past 20 years, the incidence and prevalence of type 2 diabetes mellitus (T2DM) in children and adolescents have increased, particularly in racial and ethnic minorities. Despite the rise in T2DM in children and adolescents, the pathophysiology and progression of disease in this population are not clearly understood. Youth-onset T2DM has a more adverse clinical course than is seen in those who develop T2DM in adulthood or those with T1DM. Furthermore, the available therapeutic options are more limited f… Show more
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