2005
DOI: 10.1001/archinte.165.4.447
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Type 2 Diabetes, Glycemic Control, and Continuous Positive Airway Pressure in Obstructive Sleep Apnea

Abstract: These findings suggest that SDB is pathophysiologically related to impaired glucose homeostasis, and that CPAP can be an important therapeutic approach for diabetic patients with SDB.

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Cited by 410 publications
(284 citation statements)
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References 40 publications
(49 reference statements)
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“…U ntreated obstructive sleep apnea (OSA) is associated with insulin resistance, 1,2 and some studies suggest that treatment with CPAP improves glucose control, 3,4 although this was not found in a randomized controlled trial of diabetics with sleep apnea. 5 The observation that established type 2 diabetics cannot improve glucose control when their OSA is treated with CPAP, emphasizes the importance of understanding the pathophysiology of insulin resistance associated with OSA.…”
Section: S C I E N T I F I C I N V E S T I G a T I O N Smentioning
confidence: 99%
“…U ntreated obstructive sleep apnea (OSA) is associated with insulin resistance, 1,2 and some studies suggest that treatment with CPAP improves glucose control, 3,4 although this was not found in a randomized controlled trial of diabetics with sleep apnea. 5 The observation that established type 2 diabetics cannot improve glucose control when their OSA is treated with CPAP, emphasizes the importance of understanding the pathophysiology of insulin resistance associated with OSA.…”
Section: S C I E N T I F I C I N V E S T I G a T I O N Smentioning
confidence: 99%
“…Babu e cols. estudaram 25 pacientes com DM2 descompensado (HbA1c > 7) e apnéia do sono, e observaram que houve controle do DM2 após 3 meses de tratamento com CPAP (23).…”
Section: Resistência à Insulina (Ri) E Saosunclassified
“…Recent cross-sectional and longitudinal data have shown strong and consistent associations between indices of SDB with glucose impairment and/or diabetes in adults (11,12). Causal relationships are supported by data showing that treatment of SDB is associated with improvement in indices of glucose impairment (13) or diabetes control (14). However, research that addresses the role of SDB as a risk factor for MetS in children is more limited.…”
mentioning
confidence: 97%