Tympanostomy Tube Placement and Vestibular Function in Children

Abstract

Objective To determine the effect of bilateral myringotomy with tube placement (BMT) on balance in children 4 to 7 years old Study Design Case-control study Setting Tertiary-care academic hospital Subjects and Methods Children with otitis media with effusion (OME) who were scheduled for BMT underwent rotational chair testing (RCT) and computerized dynamic posturography (CDP) preoperatively and at 1, 3, and 6 months postoperatively. Control children without a significant history of middle-ear disease were tested at the same intervals. Analysis of covariance was performed to evaluate the effect of BMT on RCT and CDP outcomes with age as a covariate. Results Seventy-two cases and fifty-six controls were enrolled. Mean age was 69 (SD 12) months for cases and 72 (SD 15) months for controls. No difference was seen between groups on RCT outcomes or sensory organization test (SOT) scores. Higher sway velocity during CDP was observed in the OME group both preoperatively and one month postoperatively. This difference was not statistically significant. There was no difference between groups three months postoperatively. At six months, the BMT group had a statistically-significant decrease in sway velocity compared to the control group. Conclusion No difference was observed between children with OME and controls in RCT or SOT scores. Gradual improvement in sway velocity was observed after BMT. At the final time-point, the groups did significantly differ in speed of sway, though the preoperative baseline difference failed to reach statistical significance. We suggest that physicians continue to inquire about balance development in patients with OME.

Predictive Factors for Vestibular Loss in Children With Hearing Loss

“…In our cohort, the number of comorbidities was too diffuse to perform any statistical analyses to determine trends on the type of comorbidity for each of the groups with vestibular loss. However, in the list of recorded comorbidities, several are associated with gross motor delay, such as OME, congenital heart defects, and neurologic disorders such as cerebral palsy (Casselbrant, Villardo, & Mandel, 2008;Cohen, Mandel, Furman, Sparto, & Casselbrant, 2011;Jones, Morgan, Shelton, & Thorogood, 2007), which suggests that, when using gross motor function to predict vestibular loss, comorbidities should be considered.…”

The Effects of Lamotrigine on Fetus Resorption and Histologic Changes in Cranium of Fetus of Albino Mice

“…In this study maternal weight in LTG treated group 'B' was reduced when compared with Control group 'A' and it was very highly significant, However Lamotrigine administration to mother has no effect on food intake, but it may be due to loss of fetuses owning to the treatment with Lamotrigine, the findings are consistent with the observation of [14], when LTG was given on day 7th and 8th at a dose of 25 mg/Kg and 50mg/kg body weight respectively. El-Sayyad et al also observed reduction in maternal body weight when lamotrigine 50 mg /Kg body weight every other day from 6th day of gestation until parturition, was given to albino rats of Wistar strain [15]. This indicates dose related toxic effects on maternal weight gain.…”

Evaluation of vestibular function in children with purulent media otitis by computer stabilometry

“…In children 3-6 years with moderate secretory otitis, the average rate of oscillation of the body according to computer stabilometry is disturbed both before and after surgery at 3 months, which is considered by the authors as a sign of latent vestibular dysfunction [16]. In the study of children 47 years with effusion in the middle ear, no differences were found with the control in the tests of Barany but found not significantly higher rocking speed according to posturography [17].…”