TXRF analysis of metals in oral fluids of patients with dental implants

Abstract

Corrosion of metals in implanted biomaterials lifetime is expected to occur. Nowadays, medical implants have good biocompatibility, present proper mechanical properties, and promote tissue regeneration; nevertheless, corrosion will eventually happen. Biological fluids are rich in chemically active ions; hence, electrochemical processes appear on the surface of the metal immediately after implantation. In order to evaluate corrosion resistance of metal implants, several studies have been carried out in artificial environments, but their results have not been always directly correlated to living systems.This work presents an indirect study of corrosion of dental implants by analyzing changes of elemental concentration of metals in oral fluids. It will also contribute to the knowledge of implant corrosion in relation to its biological environment. Degradation of the implant surface releases material to the medium, which, depending on the concentrations, can represent toxic risk, organic malfunction, pain, rejection, and so on. In order to evaluate this process, the concentrations of representative metals such as Ti, Al, and V in saliva and gingival fluids were analyzed by means of total reflection of X‐rays fluorescence analysis using synchrotron radiation.The results obtained here show that Ti‐ions present a different behavior in the oral fluids, revealing higher concentrations in gingival crevice fluid than in saliva. On the other hand, V and Al have not shown significant differences from normal levels in the oral fluids. Metal release is discussed under mechanical and chemical considerations, taking into account the oral environment of the implant. Copyright © 2014 John Wiley & Sons, Ltd.

X-Ray Fluorescence Analysis in Biology and Medicine

“…Процедура отбора проб слюны и десневых жидкостей проста, относительно недорога, имеет низкую вероятность загрязнения. Так как данные по составу слюны или другой жидкости организма дают ценную информацию в области медицины, фармакологии и контроля окружающей среды, для их исследования применяют различные методы анализа в том числе и РФА [104][105][106][107][108][109][110][111][112][113].…”

2015 Atomic Spectrometry Update – a review of advances in X-ray fluorescence spectrometry and their applications

“…Abraham et al 372 presented an indirect study of corrosion of dental implants by analysing changes in the elemental concentration of metals such as Al, Ti and V in oral uids (saliva and gingival uids) by means of SR-TXRF spectrometry. Abraham et al 372 presented an indirect study of corrosion of dental implants by analysing changes in the elemental concentration of metals such as Al, Ti and V in oral uids (saliva and gingival uids) by means of SR-TXRF spectrometry.…”

Titanium diffusion in shinbone of rats with osseointegrated implants

“…These results show large variations in the concentration of titanium (Sánchez et al ., ; Abraham et al ., ). Another survey analysed the saliva and the gingival fluid of patients with dental implants by total x‐ray fluorescence (TXRF) with synchrotron radiation (SR; Abraham et al ., ). The mean concentration of Ti measured in saliva was (3.5 ± 0.5) ppm in patients without implants and (2.8 ± 0.5) ppm in patients with implants.…”