Two-year effectiveness of zoledronic acid with or without eldecalcitol in Japanese patients with osteoporosis: A randomized prospective study

Significant change for body composition data

“…By contrast, bone mineral densitometry has established test-retest variation of 2–3% for both spine and hip [ 2 ]. Hence, the findings of another article in the same issue by Mochizuki et al [ 3 ] is quite believable as it reported changes as percentages which are clearly beyond the clinically significant range. Until this is also established for body composition data, significant changes are difficult to interpret.…”