Two-way selections for survival time of allografts in chickens.

Yamamoto, Yoshio; Okada, Ikuo

doi:10.2141/jpsa.27.337

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…Also, T-cell mediated immune response of chicken has significant variation among birds of different genetic lineage (Lamont and Smyth, 1984;Cheng and Lamont, 1988). Successful divergent selection of chickens for various T-cell functions suggests that many of these functions are highly heritable, and are often negatively correlated with body weight (Yamamoto and Okada, 1990;Afraz et al, 1994). 05 24 h = toe-web swelling at 24 hr post PHA-P injection.…”

Section: Resultsmentioning

confidence: 99%

Characterization of two Egyptian native chicken breeds using genetic and immunological parameters

Ramadan¹,

Galal

Fathi

et al. 2011

BIOTEC ANIM HUSB

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In order to identify and characterize our native chicken breeds we used two approaches, one of them is genetic and the other concerns with the immunological status of the chickens. In this study, the first 539 bases of the mtDNA D-loop region of two Egyptian native breeds (Fayoumi and Dandarawi, from El-Fayoum research station) were amplified and sequenced. The alignment results showed an approximate tandem repeat of 60-base units with the first 34 nucleotides being exact. These 34-base units were completely identical and conserved in both Egyptian and GenBank database samples. The multiple alignment results showed also that there are three transversions specific for the Egyptian breeds only. Two of them are not specific for certain breed since both of the two breeds showed the normal and mutated nucleotide. The third transversions seems to be specific to Egyptian Dandarawi breed only. The first mutation site is at the position (457) where Adenine nucleotide transversed to Cytosine nucleotide. The second mutation site is at the position (464) where Guanine nucleotide transversed to Thymine nucleotide. The third mutation site is at the position (483) where Adenine nucleotide transversed to Thymine nucleotide. With respect to immunological parameters, it could be speculated that the Fayoumi strain had hyper responders to phytohemagglutinin-P (PHA-P) injection compared to Dandarawi ones. Opposite trend was noticed for anti-SRBCs antibody response.The results may give an insight into the genetic differentiation and immunological status of the Egyptian domestic fowl. The results did not show direct relation between the two approaches used. However, the results of the two approaches can complete the identification and characterization of the chickens. Also, they could be used in future as bases for more studies.

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Section: Resultsmentioning

confidence: 99%

Characterization of two Egyptian native chicken breeds using genetic and immunological parameters

Ramadan¹,

Galal

Fathi

et al. 2011

BIOTEC ANIM HUSB

View full text Add to dashboard Cite

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Divergent selection for delayed‐type wattle reaction of domestic fowls to BCG antigen

Afraz

Yamamoto

Okada

1994

British Poultry Science

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1. Two-way selection for delayed-type hypersensitivity wattle reaction (DWR) competence to BCG antigen was carried out over 4 generations, using a flock of White Leghorn chickens. DWR was measured by intradermal injection of BCG into the wattle of chickens. 2. Selection for DWR was effective. The generation means of average selection differential, selection response and realized heritability were 1.15 mm, 0.77 mm and 0.70 respectively. Correlated responses were found in body weight, egg weight and hatchability. In all of these traits, the L line (selected for low wattle reaction) showed higher values than the H line (high reaction). 3. Specific trends in gene frequencies were observed at the major histocompatibility B and alkaline phosphatase Akp loci. 4. Significant line differences were found in graft-versus-host reaction competence and Marek's disease resistance. In both characters, the L line was higher than the H line. No line differences were found in phytohaemagglutinin response, phagocytic activity or immune responses.

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Effect of the genetic selection of turkeys for increased body weight and egg production on immune and physiological responses

et al. 1997

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Selection of poultry for fast growth rate is often accompanied by a reduction in specific immune responses or increased disease susceptibility. In this study, 17-wk-old male turkeys from each of four closed genetic lines, a randombred control (RBC) line and its subline (F) selected for increased 16-wk BW, and another RBC and its subline (E) selected for increased egg production, were tested for in vivo response to toe web inoculation with phytohemagglutinin-P (PHA-P), in vitro response of lymphocytes in whole blood to PHA-P and concanavalin A (Con A), hemolytic complement activity, differential white blood cell counts, hematology, and serum chemistry values. Fifteen male turkeys from each of two commercial lines, Com A and Com B, were also tested. The large-bodied F line birds had a lower toe web response to PHA-P, lower lymphocyte counts, and lower relative spleen weights than their smaller parent line. Body weights, total erythrocyte counts, blood urea nitrogen (BUN) levels, and in vitro mitogenic response to PHA-P and Con A were higher in the F line birds. Line E had lower hemolytic complement levels, lower relative spleen and relative bursal weights, and a higher in vitro mitogenic response to PHA-P than its parent line. The Com B line had a lower toe web response to PHA-P, and lower serum levels of gamma-glutamyltransferase and bilirubin than Com A. Line Com B had higher total RBC counts and higher levels of alanine aminotransferase (ALT) than Com A. These results support the concept that some changes in the cell-mediated immune response, as well as other physiological changes that may potentially affect immune response, appear to accompany selection for faster growth.

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Two-way selections for survival time of allografts in chickens.

Cited by 5 publications

References 17 publications

Characterization of two Egyptian native chicken breeds using genetic and immunological parameters

Characterization of two Egyptian native chicken breeds using genetic and immunological parameters

Divergent selection for delayed‐type wattle reaction of domestic fowls to BCG antigen

Effect of the genetic selection of turkeys for increased body weight and egg production on immune and physiological responses

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