Two polymorphic linker histone loci in Guinea fowl erythrocytes

Kowalski, Andrzej; Pałyga, Jan; Górnicka-Michalska, Ewa

doi:10.1016/j.crvi.2010.10.006

Cited by 13 publications

(23 citation statements)

References 45 publications

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“…Likewise, mRNA untranslated regions may influence translation by acting either as positive elements effective in increasing protein expression (Furger et al 1997) or as negative elements substantially reducing the level of the cellular protein (Calvo et al 2009). Allelic variants of histone H1 were found to fluctuate in several avian breeding flocks (Kowalski et al 1998(Kowalski et al , 2010(Kowalski et al , 2011aPalyga et al 2000;GornickaMichalska et al 2006). Changes in the distribution of histone H1 alleles can be associated with a selection process (Palyga 1998b).…”

Section: Discussionmentioning

confidence: 99%

“…Many histone H1 non-allelic subtypes may consist of allelic isoforms, thus the presence of allelic polymorphism is a distinctive feature of this histone class (Kowalski and Palyga 2012a). Since histone H1 allelic variants were shown to differ in the C-terminal domains (Palyga et al 2000;Berdnikov et al 2003;Sarg et al 2005;Gornicka-Michalska et al 2006;Bogdanova et al 2007;Villar-Garea and Imhof 2008;Kowalski et al 2011a), they could be able to interact with chromatin through the allele-specific effects as manifested by their fluctuated frequency in a given population (Palyga 1998a;Palyga et al 2000;Kowalski and Palyga 2014).…”

Section: Introductionmentioning

confidence: 99%

“…Out of eight histone H1 subtypes (H1.a, H1.a′, H1.b, H1.b′, H1.c, H1.c′, H1.d, and H1.z) identified among avian erythrocyte histone H1 (Palyga 1991), five, including H1.a in duck (Anas platyrhynchos) (Kowalski et al1998), chicken (Gallus gallus) (Gornicka-Michalska et al 2006) and quail (Coturnix japonica) (Palyga 1998a), H1.a′ in grey partridge (Perdix perdix) (Kowalski et al 2008), H1.b in quail (Palyga 1998a), duck (Palyga et al 2000) and guinea fowl (Numidea meleagris) (Kowalski et al 2011a), H1.c in pheasant (Phasianus colchicus) (Kowalski et al 2010) and guinea fowl (Kowalski et al 2011a), and H1.z in duck (Palyga et al 1993) and quail (Palyga 1998a), have been recognized to be polymorphic due to the presence of two or three electromorphs differently migrating in the polyacrylamide gels as a result of variation in their net charges and/or apparent molecular weights. Both frequent and rare allelic isoforms for the avian polymorphic histone H1 subtypes were already observed in both conservative (Kowalski et al 1998;Palyga et al 2000;Kowalski and Palyga 2014) and breeding populations (Palyga et al 1993;Palyga 1998b;Kowalski and Palyga 2014).…”

Section: Introductionmentioning

confidence: 99%

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A shift in erythrocyte histone H1 complement following selection in quail (Coturnix japonica)

et al. 2015

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This work was aimed at comparing distribution of isoforms for polymorphic histone H1 variants H1.b and H1.z and variably abundant histone H1.d subtype between quail (Coturnix japonica) population selected for a high egg yolk cholesterol content and the control birds. The isoforms of histone H1.b (H1.b1, H1.b2) and histone H1.z (H1.z1, H1.z2) differed in their apparent molecular weights judging from their differential migration rates in one-and two-dimensional SDS-polyacrylamide gels. Stained histone H1.d bands and spots in one-dimensional acetic acid-urea and two-dimensional SDS-polyacrylamide gel patterns, respectively, exhibited differential intensities among quail individuals. Histone H1. .f. = 1, P < 0.01) were found to be statistically significant among the control and selected population. In general, a moderate degree of genetic divergence (F ST equal to 0.07 and 0.1 at loci H1.b and H1.z, respectively) was observed among the control and selected quail populations. Selection may directly or indirectly affect the complement of H1 histones because of their presumably differential interactions with DNA and/or DNA-associated proteins resulting in alterations in the chromatin function.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A shift in erythrocyte histone H1 complement following selection in quail (Coturnix japonica)

et al. 2015

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“…8 C) (Pałyga et al, 1993) and three allelic variants in Muscovy duck (Fig. 8 D) (Kowalski et al, 2004) which differ either in molecular weight or molecular weight and net charge, respectively, the polymorphisms of duck, Guinea fowl and grey partridge histone H1.b (Pałyga et al, 2000;Kowalski et al, 2011aKowalski et al, , 2011b, pheasant and Guinea fowl histone H1.c (Kowalski et al, 2010;Kowalski et al, 2011a) have been detected using two-dimensional electrophoresis. A high resolution 2D-PAGE is also necessary to confirm the presence of allelic variants when some of them are faint or missing because of close migration in a direct vicinity of adjoining protein band in the first dimension polyacrylamide gel (Kowalski et al, 2010).…”

mentioning

confidence: 99%

“…This electrophoretic system is relatively straightforward and reproducible. Beside qualitative and quantitative applications (Kowalski et al, 2011a(Kowalski et al, , 2011b for protein detection and subsequent abundance estimation, the 2D-PAGE-like method may also be used on a preparative scale to enable gathering and purification of appropriate amount of the resolved protein for subsequent structural analyses including chemical cleavage and enzymatic digestion Pałyga & Neelin, 1998;Pałyga et al, 2000;Kowalski et al, 2011aKowalski et al, , 2011b as well as amino acid sequencing (Górnicka-Michalska et al, 2006) and mass spectrometry analysis (Kowalski et al, 2009).…”

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confidence: 99%

High-Resolution Two-Dimensional Polyacrylamide Gel Electrophoresis: A Tool for Identification of Polymorphic and Modified Linker Histone Components

Kowalski¹,

Pałyga²

2012

Gel Electrophoresis - Principles and Basics

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Brown Hare’s (Lepus europaeus) Histone H1 Variant H1.2 as an Indicator of Anthropogenic Stress

Kowalski

Markowski

2018

Arch Environ Contam Toxicol

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From the liver tissues of brown hare individuals that lived in two various habitats, i.e., the agricultural region with the predominant farms and the industrial area near a metallurgical plant, histones H1 were analyzed to compare their within and between population variability. Furthermore, because agricultural production emits mainly organic pollutants and metallurgical industry is a primarily source of inorganic contaminations, we wanted to check how the brown hare individuals are sensitive for both agents. Among brown hare H1 histones, the histone H1.2 was determined as heterogeneous due to its varied mobility in two-dimensional SDS–polyacrylamide gel. The obtained electrophoretic patterns contained differently moving single spots of histone H1.2 and also its double spots have a similar rate of electrophoretic mobility. Based on this, two homozygous phenotypes (slowly migrating 2a and faster moving 2b) and a heterozygous phenotype (2a2b) was distinguished. The relatively low variable (CV < 0.25) and comparably abundant (p > 0.05) histone H1.2 homozygous phenotypes form a heterozygous phenotype in a similar proportion, at a ratio approximating 0.5. Although the brown hare population originating from agricultural area displayed a slight excess of heterozygous individuals 2a2b (F = − 0.04), it was conformed to the Hardy–Weinberg assumption (χ2 = 0.035, p = 0.853). Compared with this population, a sevenfold reduced frequency of the phenotype 2b and above tenfold increase of a heterozygosity (F = − 0.53) was observed in the brown hare population inhabiting the vicinity of metallurgical plant. Therefore, this population did not fit to the Hardy–Weinberg law (χ2 = 5.65, p = 0.017). Despite the negligible genetic differentiation (FST = 0.026) between brown hare populations inhabiting areas with different anthropogenic pressure, a statistically significant difference in the distribution of their phenotypes (χ2 = 6.01, p = 0.049) and alleles (χ2 = 6.50, p = 0.013) was noted. The collected data confirm that the brown hare species is sensitive for environmental quality and may serve as a good indicator of habitat conditions related to both organic pollution emitted by agricultural activities (PIC = 0.48) and inorganic contamination originating from metallurgical processes (PIC = 0.49). These difference in the environmental quality might be assessed by estimation of genetic variability among the brown hare populations, based on the phenotypes distribution of histone H1 variant H1.2, the protein that was not so far employed as a molecular marker of anthropogenic stress.

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Two polymorphic linker histone loci in Guinea fowl erythrocytes

Cited by 13 publications

References 45 publications

A shift in erythrocyte histone H1 complement following selection in quail (Coturnix japonica)

A shift in erythrocyte histone H1 complement following selection in quail (Coturnix japonica)

High-Resolution Two-Dimensional Polyacrylamide Gel Electrophoresis: A Tool for Identification of Polymorphic and Modified Linker Histone Components

Brown Hare’s (Lepus europaeus) Histone H1 Variant H1.2 as an Indicator of Anthropogenic Stress

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