Two photon induced luminescence of BSA protected gold clusters

Raut, Sangram; Shumilov, Dmytro; Chib, Rahul; Rich, Ryan; Gryczyński, Zygmunt; Gryczyński, Ignacy

doi:10.1016/j.cplett.2013.01.028

Cited by 19 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Due to herceptin′s therapeutic effect, the conjugate was simultaneously used for targeted imaging and therapy 38b. Even deeper tissue penetration would be possible if two‐photon excitation was used for the AuNC‐BSA 39…”

Section: Protein‐directed Approachesmentioning

confidence: 99%

π‐Expanded α,β‐Unsaturated Ketones: Synthesis, Optical Properties, and Two‐Photon‐Induced Polymerization

et al. 2014

View full text Add to dashboard Cite

A library of π-expanded α,β-unsaturated ketones was designed and synthesized. They were prepared by a combination of Wittig reaction, Sonogashira reaction, and aldol condensation. It was further demonstrated that the double aldol condensation can be performed effectively for highly polarized styrene- and diphenylacetylene-derived aldehydes. The strategic placement of two dialkylamino groups at the periphery of D-π-A-π-D molecules resulted in dyes with excellent solubility. These ketones absorb light in the region 400-550 nm. Many of them display strong solvatochromism so that the emission ranges from 530-580 nm in toluene to the near-IR region in benzonitrile. Ketones based on cyclobutanone as central moieties display very high fluorescence quantum yields in nonpolar solvents, which decrease drastically in polar media. Photophysical studies of these new functional dyes revealed that they possess an enhanced two-photon absorption cross section when compared with simpler ketone derivatives. Due to strong polarization of the resulting dyes, values of two-photon absorption cross sections on the level of 200-300 GM at 800 nm were achieved, and thanks to that as well as the presence of the keto group, these new two-photon initiators display excellent performance so that the operating region is 5-75 mW in some cases.

show abstract

Section: Protein‐directed Approachesmentioning

confidence: 99%

π‐Expanded α,β‐Unsaturated Ketones: Synthesis, Optical Properties, and Two‐Photon‐Induced Polymerization

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Currently, considerable research efforts are directed towards investigation of Au NCs synthesis [4][5][6][7][8][9][10], structure [7,11,12], optical properties [4,[13][14][15][16], photostability [17][18][19][20][21] and possible applications for material sensing [5,[22][23][24] as fluorescence [25,26] and dual-modality imaging contrast agents [27,28]. However, colloidal stability, photostability, dependence of optical properties on temperature, interaction of BSA-Au NCs with biomolecules are still poorly investigated.…”

Section: Introductionmentioning

confidence: 99%

Protein stabilized Au nanoclusters: spectral properties and photostability

Poderys¹,

Matulionytė-Safinė²,

Rupšys³

et al. 2016

Lith. J. Phys.

View full text Add to dashboard Cite

Bovine serum albumin stabilized gold nanoclusters (BSA-Au nanoclusters) have been widely studied due to their possible applications in biomedicine as sensors, fluorescent or multi-modality markers, and therapeutic agents. Synthesis and optical properties of these nanoclusters have been extensively investigated; however, there is still very little data on photostability of BSA-Au nanoclusters. Photostability of BSA-Au nanoclusters is of major importance for a variety of applications, such as material sensing and fluorescence imaging. Herein we demonstrate that after synthesis the BSA-Au solution has two photoluminescence (PL) bands peaking at 468 and 660 nm. Nevertheless, a different behaviour of the PL bands at 468 and 660 nm upon irradiation indicates that only band at 660 nm is related to PL of Au nanoclusters. BSA-Au nanoclusters exhibit great colloidal stability and do not undergo irreversible changes when heated up to 65 °C. However, irradiation of BSA-Au nanoclusters causes a wavelength dependent decrease of intensity and a hypsochromic shift of the PL band at 660 nm which is proportional to the delivered dose. The shift of the PL band at 660 nm could occur due to loss of several gold atoms in Au nanoclusters and/or due to deterioration of a nanoparticle coating layer. We have also demonstrated that the photostability of BSA-Au nanoclusters increases in the cell growth medium.

show abstract

“…Today. 2018; Volume 1, Article Number 1001 DOI: 10.31716/frt.201801001 absorption followed by blue 57 to red to near-infrared photoluminescence 58 . Using (bio)organic thiolate templates, further enhancement can be achieved by the increasing rigidity of the metal-sulfur interface.…”

Section: Discussionmentioning

confidence: 99%

Atomically precise clusters of gold and silver: A new class of nonlinear optical nanomaterials

Antoine

2018

Front. Res. Today

View full text Add to dashboard Cite

Functional ligand-protected metal cluster nanomaterials with increased two-photon absorption and two-photon excited emission might result in new technologies within the fields of bio-imaging applications. During this article, I review the two-photon absorption/emission properties of atomically precise ligand-protected silver and gold nanoclusters, coined "ligand-core" NLO-phores. This includes quantumchemical methodologies using time-dependent density theory. I will analyze physical phenomena and trends resulting in giant two-photon absorption/emission responses of a number of series of model nanoclusters. I will then focus my review on the effects of the relaxation pathways within the linear and nonlinear optical regime, similarly as innovative ways aiming at enhancing their two-photon emission responses.

show abstract

Two photon induced luminescence of BSA protected gold clusters

Cited by 19 publications

References 24 publications

π‐Expanded α,β‐Unsaturated Ketones: Synthesis, Optical Properties, and Two‐Photon‐Induced Polymerization

π‐Expanded α,β‐Unsaturated Ketones: Synthesis, Optical Properties, and Two‐Photon‐Induced Polymerization

Protein stabilized Au nanoclusters: spectral properties and photostability

Atomically precise clusters of gold and silver: A new class of nonlinear optical nanomaterials

Contact Info

Product

Resources

About