Six new compounds were isolated from the whole plant of Sonchus uliginosus, including three eudesmane-type sesquiterpenoids (1b,6a)-1,6,14-trihydroxyeudesm-3-en-12-oic acid g-lactone (1), (1b,6a)-1,6,14-trihydroxyeudesma-3,11(13)-dien-12-oic acid g-lactone (2), and (1b,6a)-1,6-dihydroxy-14-O-[(4-hydroxyphenyl)acetyl]eudesma-3,11(13)-dien-12-oic acid g-lactone (3), and three phenylpropane derivatives, 4-hydroxy-g,3,5-trimethoxybenzenepropanol (6), g,3,4,5-tetramethoxybenzenepropanol (7), and g,3,4,5-tetramethoxybenzenepropanol acetate (8), together with the two known compounds 4 and 5. The new structures were elucidated by means of spectroscopic methods, such as IR, EI-MS, HR-ESI-MS, 1D-and 2D-NMR, and by comparison of the spectroscopic data with those reported for structurally related compounds.Introduction. -The genus Sonchus, representing 8 species in China, has long been used as folk medicine for the treatment of fever, stasis, and inflammation, as well as for detoxication and mobilization of blood circulation [1]. In some species, eudesmanolides