Abstract. The horizontal microchannel with the height of 50 micrometres and width of 40 mm of a rectangular cross-section has been used to study two-phase flow. The classical patterns of two-phase flow in the channel (bubble, stratified, churn , jet, and annular) have been detected. Experimental information allows us to define the characteristics of the regimes and to determine precisely the boundaries between the patterns of the two-phase flows.