Yamamoto K, Kubo T, Matsunaga T. Vugul und .syrnpthctic nrrre uctii;itie.s inJluencerl bj. posterior cerebral circulutions in rabbits. Acta Otolaryngol (Stockh) 1993: Suppl 506: 30-33.Vagal and sympathetic nervous activities in the rabbit were recorded while vertebral blood flow was partially blocked by the injection of adenosine S'dphosphate (ADP: platelet aggregator). When a small dose of ADP (0.2mg/kg) was administrated into a unilateral vertebral artery, sympathetic nerve (SN) activity increased, and its magnitude was inversely correlated with the extent of the decrease in blood pressure (BP). A larger dose ( 2 mg/kg) of ADP suppressed SN activity on the injected side. whereas the change was small on the non-injected side. Vagal nerve (VN) activity showed a monophasic excitatory response on both sides, although the change was larger on the injected than on the non-injected side. As a result. asymmetry in autonomic nerve activity was more distinct in SN than in VN. The present study demonstrated that asymmetry of autonomic nervous function can result from changes in blood flow in the cerebellum and brainstem. Kej. ivorcls: .sytnpor/teiic nerue. iqgul ni'ru~, microemboli. A DP. Acta Otolaryngol Downloaded from informahealthcare.com by Nyu Medical Center on 07/13/15 For personal use only. Acta Otolaryngol Downloaded from informahealthcare.com by Nyu Medical Center on 07/13/15 For personal use only.