“…Making the definitive diagnosis of RRD-CD can be challenging because broad categories of infectious, neoplastic, or inflammatory need to be considered as well. 35 The differential diagnosis includes traumatic or postsurgical hypotony, melanoma, posterior scleritis, uveal effusion syndrome, and choroidal metastasis. Preoperative ophthalmologic examination of the fundus and choroidal vortex veins to identify choroidal involvement may be limited by active intraocular inflammation, poor pupillary dilation, posterior synechiae, and media opacity.…”